Evidence map›Paper›PMID 33934541›Full record

ArticleESC heart failure2021

A decrease in tricuspid regurgitation pressure gradient associates with favorable outcome in patients with heart failure.

Yuta Seko, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Masayuki Shiba, Erika Yamamoto, Yusuke Yoshikawa and 14 more

Abstract read
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Left bundle branch area pacing decreased the pressure gradient and severity of tricuspid regurgitation compared with right ventricular pacing.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Yuta SekoDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Takao KatoDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Takeshi MorimotoClinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan.
Hidenori YakuDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Yasutaka InuzukaCardiovascular Medicine, Shiga General Hospital, Moriyama, Japan.
Yodo TamakiDivision of Cardiology, Tenri Hospital, Tenri, Japan.
Neiko OzasaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Masayuki ShibaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Erika YamamotoDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Yusuke YoshikawaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Takeshi KitaiDepartment of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Yugo YamashitaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Moritake IguchiDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Kazuya NagaoDepartment of Cardiology, Osaka Red Cross Hospital, Osaka, Japan.
Yuichi KawaseDepartment of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan.
Takashi MorinagaDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Japan.
Mamoru ToyofukuDepartment of Cardiology, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan.
Yutaka FurukawaDepartment of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Kenji AndoDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Japan.
Kazushige KadotaDepartment of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan.
Yukihito SatoDepartment of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan.
Koichiro KuwaharaDepartment of Cardiovascular Medicine, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.
Takeshi KimuraDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
KCHF Study Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsAlthough the prognostic impact of the high tricuspid regurgitation pressure gradient (TRPG) has been investigated, the association of the decrease in TRPG during follow-up with clinical outcomes in heart failure (HF) has not been previously studied. The aim of this study was to investigate the association of a decrease in TRPG between hospitalization and 6 month visit with subsequent clinical outcomes in patients with acute decompensated HF (ADHF). METHODS AND

resultsAmong 721 patients with available TRPG data both during hospitalization and a subsequent 6 month visit, the study population was divided into two groups: a decrease in TRPG group (>10 mmHg decrease at 6 month visit) (N = 179) and no decrease in TRPG group (N = 542). The primary outcome measure was a composite of all-cause death or HF hospitalization. The cumulative 6 month incidence of primary outcome measure was significantly lower in the decrease in TRPG group than in the no decrease in TRPG group (12.2% vs. 18.7%, P = 0.02). After adjusting for confounders, there was a significantly lower risk in decrease in TRPG group than in the no decrease in TRPG group for the measured primary outcome (hazard ratio: 0.56, 95% confidence interval 0.32-0.93, P = 0.02). The lower risk in decrease in TRPG group was not different among the basal TRPG values.

conclusionsHeart failure patients with a decrease in TRPG at 6 months after discharge from ADHF hospitalization had lower subsequent risk of all-cause death and HF hospitalization than those without a decrease in TRPG, regardless of TRPG values.

Indexed as

Heart FailureTricuspid Valve InsufficiencyHospitalizationHumansIncidencePrognosisHeart failureHospitalizationMortalityProspectiveTricuspid regurgitation pressure gradient

Identifiers

PMID33934541
PMCPMC8318484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.