ArticleMaxillofacial plastic and reconstructive surgery2021
Functional and electron-microscopic changes after differential traction injury in the sciatic nerve of a rat.
Article in Maxillofacial plastic and reconstructive surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Intraoperative six-axis loads during direct anterior approach total hip arthroplasty using a leg positioner: quantitative patterns across manoeuvres.International orthopaedics · 2026Article
- Electrical or magnetic nerve stimulation enhance the BoNT/A-mediated muscle paralysis.Journal of neuroengineering and rehabilitation · 2026Article
- Histological and Functional Changes Induced by Compression and Decompression Develop Slower in Diabetic Nerves Than in Nondiabetic Nerves.BioMed research international · 2026Article
- Intranasal adipose-derived stem cells mitigate cuprizone-induced demyelination in mouse corpus callosum by modulating oligodendrocyte and microglial marker expression: histological and ultrastructural insights.Journal of molecular histology · 2025Article
- What Is the Sequence of Mechanical and Structural Failure During Stretch Injury in the Rat Median Nerve? The Neuroclasis Classification.Clinical orthopaedics and related research · 2025Article
- Low-intensity sciatic nerve-stretch injury increases nociception, anxiety-like behaviors, and astrocyte activity in male Wistar rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- Therapeutic Potential of Vitamin B Complex in Peripheral Nerve Injury Recovery: An Experimental Rat Model Study.Medicina (Kaunas, Lithuania) · 2024Article
- A Prospective Study of Electromyographic Amplitude Changes During Intraoperative Neural Monitoring for Open Thyroidectomy.World journal of surgery · 2023Article
- Surgically Induced Demyelination in Rat Sciatic Nerve.Brain sciences · 2023Article
- The effect of FK506 (tacrolimus) loaded with collagen membrane and fibrin glue on promotion of nerve regeneration in a rat sciatic nerve traction injury model.Maxillofacial plastic and reconstructive surgery · 2022Article
- Construction and effect evaluation of different sciatic nerve injury models in rats.Translational neuroscience · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring maxillofacial trauma or oral cancer surgery, peripheral nerve might be damaged by traction injury. The purpose of this study was to evaluate functional and histomorphometric changes after traction nerve injury in the sciatic nerve of a rat model.
methodsA total of 24 Sprague-Dawley rats were equally divided into three groups: unstretched (sham/control, group A), stretched with 0.7N (group B) and 1.5N (group C). Traction injury was performed for 10 min in B and C groups. Functional recovery of the sciatic nerve was evaluated by walking track analysis, toe spread test, and pinprick test 2 weeks after injury. The weight of gastrocnemius muscles of both sides was measured to evaluate weight ratio (ipsilateral/contralateral). Total number of axons, axon fiber size, myelin thickness, G-ratio, axon number/mm
resultsThe sciatic function indexes were -11.48±4.0, -15.11±14.84, and -49.12±35.42 for groups A, B, and C, respectively. Pinprick test showed 3.0, 2.86±0.38, and 1.38±0.52 for A, B, and group C. Muscle weight ratios were 0.98±0.13 for group A, 0.70±0.10 for group B, and 0.54±0.05 for group C. There were significant differences in toe spread test, pinprick test, and muscle weight ratio between control group and experimental group (p<0.001). In the experimental group, fiber number, fiber size, G-ratio, fiber number/mm
conclusionThe present study demonstrated that the nerve traction injury in the rat sciatic nerve damaged the motor and sensory function and axonal integrity. The amount of functional nerve damage was proportional to the amount of traction power and dependent on the initial tensile strengths (0.7N and 1.5N).
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