Evidence map›Paper›PMID 33934202›Full record

ArticlePediatric cardiology2021

Finding the Optimal Timing for Repair of Standard Tetralogy of Fallot: Analysis of Cardiac Magnetic Resonance and Echocardiography Parameters Related to Intermediate Term Outcomes in a Pediatric Population.

Esther Aurensanz Clemente, Álex Pérez Casares, Pablo Ruiz Frontera, Jose M Caffarena Calvar, Joan Sanchez de Toledo

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Pediatric cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05288894 (Multicenter Italian Registry From the Italian Pediatric Cardiology Society), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05288894 recruitingnot on this map

Multicenter Italian Registry From the Italian Pediatric Cardiology Society (SICP) Working Group (WG) on CMR/CT for the Repaired Tetralogy of Fallot

Typeobservational_patient_registrySponsorAzienda Ospedaliero, Universitaria Ospedali RiunitiRan2021 to 2027Enrolled150ConditionsTetralogy of Fallot, Cardiac Death, Sudden, Cardiac Arrhythmia, Cardiac EventArmsCardiac magnetic resonance imaging
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Esther Aurensanz ClementePediatric Cardiology Department, Sant Joan de Déu Children Hospital, C/Passeig Sant Joan de Deu, s/n, 08950, Esplugues, Barcelona, Spain. eaurensanz@sjdhospitalbarcelona.org.ORCID http://orcid.org/0000-0002-1521-9553
Álex Pérez CasaresPediatric Cardiology Department, Sant Joan de Déu Children Hospital, C/Passeig Sant Joan de Deu, s/n, 08950, Esplugues, Barcelona, Spain.
Pablo Ruiz FronteraIntensive Care Unit, Cardiac Institute Quiron Salud Teknon, Barcelona, Spain.
Jose M Caffarena CalvarCardiac Surgery Department, Sant Joan de Déu Children Hospital, Barcelona, Spain.
Joan Sanchez de ToledoPediatric Cardiology Department, Sant Joan de Déu Children Hospital, C/Passeig Sant Joan de Deu, s/n, 08950, Esplugues, Barcelona, Spain.
Hospital Sant Joan de Déu Barcelona · ESHospital Quirón Teknon · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRight ventricular (RV) dilatation is the determining prognostic factor in the long-term follow up of patients with repaired Tetralogy of Fallot (TOF). The objective of this study is to analyze whether the results vary depending on the timing of the complete repair and on the surgical technique applied. MATERIAL-

methodsThis is a retrospective longitudinal study in which patients with standard TOF were divided into 3 groups depending on their age at surgical repair: group 1 = Early repair (n = 12,1-8 months), group 2 = Late repair (n = 26, > 8 months), and group 3 = Late repair with previous palliative surgery (n = 17, > 8 months). Clinical, echocardiographic and cardiac magnetic resonance (CMR) data from patients that had received complete reparative surgery in our institution from January 2000 to March 2014 were analyzed and compared.

results55 patients with echocardiogram and CMR studies (13.39 ± 3.59 years) were reviewed. All patients had at least moderate pulmonary regurgitation (PR). We observed a positive correlation between PR and right ventricular end-diastolic volume (r

conclusionsAlthough all patients from our cohort had significant PR, age at surgery was not related to RV or pulmonary trunk dilatation. Previous palliative surgery was associated with more severe right ventricular dilatation and longer hospital stays. No differences were observed between early and late repair groups. Our study suggests that postponing TOF repair to a late stage does not improve the degree of PR or long-term morbidity from RV dilatation. Palliative surgery should be avoided if possible.

Indexed as

Cardiac Surgical ProceduresCohort StudiesEchocardiographyFemaleHeart VentriclesHumansInfantLongitudinal StudiesMagnetic Resonance Imaging, CineMalePulmonary CirculationRetrospective StudiesTetralogy of FallotTime FactorsTime-to-TreatmentTreatment OutcomeCardiac magnetic resonancePalliative surgeryPulmonary regurgitationRight ventricle functionSurgical repairTetralogy of Fallot

Identifiers

PMID33934202
OpenAlexW3158712448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.