ArticleAnalytical and bioanalytical chemistry2021
Monitoring of the decreased mitochondrial viscosity during heat stroke with a mitochondrial AIE probe.
Article in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 38 citations in OpenAlex.
- Fluorescent TAPY-bodipy dyads as tools for imaging fungal mitochondria by confocal microscopy and flow cytometry.Analytical and bioanalytical chemistry · 2026Article
- Organic Fluorophores Conjugated with Pyridinium Acceptor: A Review on Design, Synthesis, and Application in Mitochondrial Imaging.Current pharmaceutical design · 2026Review
- Overexpression of Parkin promotes the protective effect of mitochondrial autophagy on the lung of rats with exertional heatstroke.Journal of intensive medicine · 2025Article
- Protection of Parkin over-expression on lung in rats with exertional heat stroke by activating mitophagy.BMC pulmonary medicine · 2024Article
- Activation of Pink1/Parkin-mediated mitochondrial autophagy alleviates exertional heat stroke-induced acute lung injury in rats.Clinical hemorheology and microcirculation · 2024Article
- Surfactant-chaperoned donor-acceptor-donor NIR-II dye strategy efficiently circumvents intermolecular aggregation to afford enhanced bioimaging contrast.Chemical science · 2022Article
- Super-stable cyanine@albumin fluorophore for enhanced NIR-II bioimaging.Theranostics · 2022Article
- Lessons From Heat Stroke for Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.Frontiers in neurology · 2021Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Heat stroke is a fatal condition which usually results in central nervous system dysfunction, organism damage and even death. The relationship between heat stroke and mitochondria is still relatively unknown due to a lack of suitable tools. Herein, an aggregation-induced emission (AIE) probe CSP, by introducing a pyridinium cation as the mitochondria-targeted group to an AIE active core cyanostilbene skeleton, is highly sensitive to viscosity changes due to the restriction of intramolecular motion (RIM) and inhibition of twisted intramolecular charge transfer (TICT) in high-viscosity systems. As expected, with the viscosity increasing from 0.903 cP (0% glycerol) to 965 cP (99% glycerol), CSP exhibited a significant enhancement (more than 117-fold) in fluorescence intensity at 625 nm, with an excellent linear relationship between log I
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Registered trials
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