Evidence map›Paper›PMID 33933928›Full record

ArticleJournal of psychiatric research2021

Cannabis use disorder, anger, and violence in Iraq/Afghanistan-era veterans.

Kirsten H Dillon, Elizabeth E Van Voorhees, Eric B Elbogen, Jean C Beckham, VA Mid-Atlantic MIRECC Workgroup, Patrick S Calhoun

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Understanding the Role of Endocannabinoids in Posttraumatic Stress Disorder.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kirsten H DillonDurham VA Health Care System, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, NC, USA. Electronic address: kirsten.dillon@va.gov.
Elizabeth E Van VoorheesDurham VA Health Care System, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, NC, USA.
Eric B ElbogenDuke University Medical Center, Durham, NC, USA; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, NC, USA; National Center on Homelessness Among Veterans, Washington, DC, USA.
Jean C BeckhamDurham VA Health Care System, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, NC, USA.
VA Mid-Atlantic MIRECC WorkgroupVA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, NC, USA.
Patrick S CalhounDurham VA Health Care System, Durham, NC, USA; Duke University Medical Center, Durham, NC, USA; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, NC, USA; VA Center for Health Services Research in Primary Care, Durham, NC, USA.
Durham VA Health Care System · USDurham VA Medical Center · US

Funding

Neurosteroids in PTSD - Biomarkers to TherapeuticsIK2CX001397 · VA · DURHAM VA MEDICAL CENTER · PI SZABO, STEVEN · 2018 to 2021
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Developing a Mobile Intervention for Veterans with Posttraumatic Stress Disorder and Problematic AngerIK2RX002965 · VA · DURHAM VA MEDICAL CENTER · PI DILLON, KIRSTEN HAWKINS · 2019 to 2023
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CSR&D Research Career Scientist AwardIK6BX003777 · VA · DURHAM VA MEDICAL CENTER · PI BECKHAM, JEAN C. · 2017 to 2023
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BLRD VA IK6 BX003777CSRD VA IK2 CX001397RRD VA IK2 RX002965
6 · The paper itself

Abstract

An association has been found between cannabis use disorder (CUD) and violence in several clinical populations, including veterans with posttraumatic stress disorder (PTSD), and there is evidence that CUD has been increasing among veterans since September 11, 2001. There is also evidence that some veterans may be attempting to self-medicate psychological problems including PTSD and aggression with cannabis, despite the lack of safety and efficacy data supporting this use. To date, however, the association between CUD and aggression has yet to be examined in a large, non-clinic sample of veterans. The present study examined the association between cannabis use disorder, anger, aggressive urges, and difficulty controlling violence in a large sample of Iraq/Afghanistan-era veterans (N = 3028). Results of multivariate logistic regressions indicated that current CUD was significantly positively associated with difficulty managing anger (OR = 2.93, p < .05), aggressive impulses/urges (OR = 2.74, p < .05), and problems controlling violence in past 30 days (OR = 2.71, p < .05) even accounting for demographic variables, comorbid symptoms of depression and PTSD, and co-morbid alcohol and substance use disorders. Lifetime CUD was also uniquely associated with problems controlling violence in the past 30 days (OR = 1.64, p < .05), but was not significantly associated with difficulty managing anger or aggressive impulses/urges. Findings indicated that the association between CUD and aggression needs to be considered in treatment planning for both CUD and problems managing anger and aggressive urges, and point to a critical need to disentangle the mechanism of the association between CUD and violence in veterans.

Indexed as

CannabisMarijuana AbuseStress Disorders, Post-TraumaticVeteransAfghanistanAngerHumansIraqIraq War, 2003-2011ViolenceAggressionAngerCannabis use disorderVeteransViolence

Identifiers

PMID33933928
PMCPMC8954688
OpenAlexW3156553511

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.