Evidence map›Paper›PMID 33933837›Full record

ArticleEuropean journal of radiology2021

Evaluating renal lesions using deep-learning based extension of dual-energy FoV in dual-source CT-A retrospective pilot study.

Fides R Schwartz, Darin P Clark, Yuqin Ding, Juan Carlos Ramirez-Giraldo, Cristian T Badea, Daniele Marin

Abstract read
In one paragraph

Article in European journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Systematic Review on Learning-based Spectral CT.IEEE transactions on radiation and plasma medical sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fides R SchwartzDuke University Health System, Department of Radiology, 2301 Erwin Road, Box 3808, Durham, NC, 27710, United States. Electronic address: fides.schwartz@duke.edu.
Darin P ClarkQuantitative Imaging and Analysis Lab, Department of Radiology, Duke University, Durham, NC, 27710, United States. Electronic address: darin.clark@duke.edu.
Yuqin DingDuke University Health System, Department of Radiology, 2301 Erwin Road, Box 3808, Durham, NC, 27710, United States; Department of Radiology, Zhongshan Hospital, Fudan University; Shanghai Institute of Medical Imaging, Shanghai, 200032, People's Republic of China. Electronic address: yuqin.ding@duke.edu.
Juan Carlos Ramirez-GiraldoCT R&D Collaborations at Siemens Healthineers, 2424 Erwin Road - Hock Plaza, Durham, NC, 27705, United States. Electronic address: juancarlos.ramirezgiraldo@siemens-healthineers.com.
Cristian T BadeaQuantitative Imaging and Analysis Lab, Department of Radiology, Duke University, Durham, NC, 27710, United States. Electronic address: Cristian.badea@duke.edu.
Daniele MarinDuke University Health System, Department of Radiology, 2301 Erwin Road, Box 3808, Durham, NC, 27710, United States. Electronic address: daniele.marin@duke.edu.

Funding

The Duke Preclinical Research Resources for Quantitative Imaging BiomarkersU24CA220245 · NCI · DUKE UNIVERSITY · PI BADEA, CRISTIAN T · 2017 to 2021
$2.8M
Development of a New Generation Micro-CT imaging for Functional and Molecular Imaging of CancerR01CA196667 · NCI · DUKE UNIVERSITY · PI BADEA, CRISTIAN T · 2015 to 2019
$2.3M
Cardiac photon counting CT and its application in studying interactions between Alzheimer's and heart diseaseRF1AG070149 · NIA · DUKE UNIVERSITY · PI BADEA, CRISTIAN T · 2021 to 2022
$2.1M
Multiorgan Photon Counting CT and Machine Learning to Elucidate Aging Mechanisms and InterventionsR01AG070149 · NIA · DUKE UNIVERSITY · PI CRISTIAN T BADEA, Alexandra Badea · 2024 to 2026
$2.1M
NCI NIH HHS R01 CA196667NCI NIH HHS U24 CA220245NIA NIH HHS R01 AG070149NIA NIH HHS RF1 AG070149
6 · The paper itself

Abstract

purposeDual-source (DS) CT, dual-energy (DE) field of view (FoV) is limited to the size of the smaller detector array. The purpose was to establish a deep learning-based approach to DE extrapolation by estimating missing image data using data from both tubes to evaluate renal lesions.

methodA DE extrapolation deep-learning (DEEDL) algorithm had been trained on DECT data of 50 patients using a DSCT with DE-FoV = 33 cm (Somatom Flash). Data from 128 patients with known renal lesions falling within DE-FoV was retrospectively collected (100/140 kVp; reference dataset 1). A smaller DE-FoV = 20 cm was simulated excluding the renal lesion of interest (dataset 2) and the DEEDL was applied to this dataset. Output from the DEEDL algorithm was evaluated using ReconCT v14.1 and Syngo.via. Mean attenuation values in lesions on mixed images (HU) were compared calculating the root-mean-squared-error (RMSE) between the datasets using MATLAB R2019a.

resultsThe DEEDL algorithm performed well reproducing the image data of the kidney lesions (Bosniak 1 and 2: 125, Bosniak 2F: 6, Bosniak 3: 1 and Bosniak 4/(partially) solid: 32) with RSME values of 10.59 HU, 15.7 HU for attenuation, virtual non-contrast, respectively. The measurements performed in dataset 1 and 2 showed strong correlation with linear regression (r

conclusionThis DEEDL algorithm can be used to reconstruct a full dual-energy FoV from restricted data, enabling reliable HU value measurements in areas not covered by the smaller FoV and evaluation of renal lesions.

Indexed as

Deep LearningRadiography, Dual-Energy Scanned ProjectionContrast MediaHumansKidneyPilot ProjectsReproducibility of ResultsRetrospective StudiesTomography, X-Ray ComputedContrast MediaCysticDeep learningKidney diseasesKidney neoplasmsMultidetector computed tomography

Identifiers

PMID33933837
PMCPMC8204258

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.