ArticleThe Science of the total environment2021
Interconversion between methoxylated, hydroxylated and sulfated metabolites of PCB 3 in whole poplar plants.
Article in The Science of the total environment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Complex roles for sulfation in the toxicities of polychlorinated biphenyls.Critical reviews in toxicology · 2024Review
- Review
- PCB Sulfates in Serum from Mothers and Children in Urban and Rural U.S. Communities.Environmental science & technology · 2022Article
- Hydroxylated Polychlorinated Biphenyls Are Emerging Legacy Pollutants in Contaminated Sediments.Environmental science & technology · 2022Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Methoxylated polychlorinated biphenyls (MeO-PCBs) are overlooked metabolites of PCBs. In general, they are more toxic to plants than their parent congeners. However, information on the fate of MeO-PCBs and the relationship between methoxylated, hydroxylated and sulfated metabolites of PCBs in plants is scarce. In this work, poplar plants (Populus deltoides × nigra, DN34) were hydroponically and separately exposed to 4'-methoxy-4-monochlorobiphenyl (4'-MeO-PCB 3) and 4'-PCB 3 sulfate for 10 days to investigate the uptake, translocation and metabolism of MeO-PCBs and the relationship between methoxy-PCBs, hydroxyl-PCBs and PCB sulfates within plants. Results showed that 4'-MeO-PCB 3 and 4'-PCB 3 sulfate were taken up by the roots of poplar plants and translocated from roots to shoots and leaves. 4'-OH-PCB 3 and 4'-PCB 3 sulfate were identified as the hydroxylated metabolite and sulfate metabolite of 4'-MeO-PCB 3 in poplar, respectively. In the backward reaction, 4'-OH-PCB 3 and 4'-MeO-PCB 3 were found as metabolites of 4'-PCB 3 sulfate. For exposure groups, the yields of 4'-OH-PCB 3 produced from 4'-MeO-PCB 3 and 4'-PCB 3 sulfate were 1.29% and 0.13% respectively. The yield of 4'-PCB 3 sulfate which originated from 4'-MeO-PCB 3 in wood and root samples of exposure groups was only 0.02%. Only 0.04% of the initial mass of 4'-PCB 3 sulfate was transformed to 4'-MeO-PCB 3 in the exposure groups. The sulfation yield of 4'-OH-PCB 3 was higher than hydrolysis yield of 4'-PCB 3 sulfate, indicating that formation of PCB sulfates was predominant over the reverse reaction, the formation of hydroxy-PCBs. These results provide new perspective on the transport, metabolism, and fate of MeO-PCBs, and also help to better understand sources of OH-PCBs and PCB sulfates in the environment. This study provides the first evidence of interconversion of sulfate metabolites from methoxy-PCBs and methoxy-PCBs from PCB sulfates.
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