SynthesisJournal of pain and symptom management2021
The Challenges of Enrollment and Retention: A Systematic Review of Psychosocial Behavioral Interventions for Patients With Cancer and Their Family Caregivers.
Synthesis in Journal of pain and symptom management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Pooled it
- Systematic review of psychosocial interventions for adult cancer patients and their family caregivers in Sub-Saharan Africa.Global public health · 2023Pooled it
- Family-based psychosocial interventions for adult Latino patients with cancer and their caregivers: A systematic review.Frontiers in psychology · 2023Pooled it
- Palliative Care Coaching for Family Caregivers of Patients With Advanced Cancer: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Trial
- Challenges and Approaches to Recruitment for and Retention in a Dyad-Focused eHealth Intervention During COVID-19: Randomized Controlled Trial.Journal of medical Internet research · 2024Trial
- Feasibility of a digital palliative care intervention (Convoy-Pal) for older adults with heart failure and multiple chronic conditions and their caregivers: a waitlist randomized control trial.BMC palliative care · 2024Trial
- Trial
- Acceptance and commitment therapy for patient fatigue interference and caregiver burden in advanced gastrointestinal cancer: Results of a pilot randomized trial.Palliative medicine · 2022Trial
- Trial
- An Early Palliative Care Telehealth Coaching Intervention to Enhance Advanced Cancer Family Caregivers' Decision Support Skills: The CASCADE Pilot Factorial Trial.Journal of pain and symptom management · 2022Trial
- Addressing Existential Distress Through Compassion: Feasibility and Preliminary Effects of Compassion With You (COMwithU), a Compassion-Based Intervention for Patients With Cancer.Psycho-oncology · 2026Article
- Turning Points in Prognostic Uncertainty Across the Disease Trajectory For Emerging and Young Adult Caregivers of a Parent with Advanced Cancer.SSM. Qualitative research in health · 2026Article
- Community Implementation of a Clinician and Caregiver Co-Led Programme to Promote the Wellbeing of Family Caregivers of Individuals With Intellectual and Developmental Disabilities.Journal of applied research in intellectual disabilities : JARID · 2026Article
- The CARING intervention for neuro-oncology family caregivers: Primary outcomes from an abbreviated randomized controlled trial.Neuro-oncology practice · 2026Article
- Evaluating the Process of Patient Engagement: Insights from a Mixed-Methods Evaluation of a Cancer Center Patient Advisory Group.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- Article
- Associations of Critical Relationships With Distress and Burden in Caregivers of Patients With Brain Tumor.Psycho-oncology · 2025Article
- The CARING intervention for neuro-oncology family caregivers: Randomized controlled trial feasibility, eSNAP/caregiver navigation engagement, and acceptability.Neuro-oncology practice · 2025Article
- Caring-Healing Modalities for Emotional Distress and Resilience in Persons with Cancer: A Scoping Review.Nursing reports (Pavia, Italy) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
contextPsychosocial behavioral interventions (PBIs) that target patients with cancer and their caregivers face challenges in participant enrollment and retention.
objectives1) Describe characteristics of the patient-caregiver PBI studies; 2) examine participant enrollment and retention rates; 3) identify factors influencing participant enrollment and retention rates; and 4) explore the strategies to promote enrollment and retention rates.
methodsWe identified randomized controlled trials that tested PBIs among adult patients with cancer and caregivers in five electronic databases. We conducted narrative and quantitative analyses to synthesize our findings.
resultsAmong 55 qualified studies reviewed, most tested the efficacy of PBIs (n = 42) and used two study arms (n = 48). In-person meeting was the most common PBI delivery mode. The primary outcomes included quality of life, physical health, and symptoms. The average of enrollment rates of patient-caregiver dyads was 33% across studies (range 8%-100%; median = 23%). The average retention rate at the end of follow-ups was 69% (range 16%-100%; median = 70%). The number of study arms, recruitment method, type of patient-caregiver relationship, and intervention duration influenced enrollment rates. Study design (efficacy vs. pilot), follow-up duration, mode of delivery, type of relationship, and intervention duration influenced retention rates. Sixteen studies reported retention strategies, including providing money/gift cards upon study completion and/or after follow-up survey, and excluding patients with advanced cancer.
conclusionResearchers need to incorporate effective strategies to optimize enrollment and retention in patient-caregiver PBI trials. Researchers need to report detailed study processes and PBI information to improve research transparency and increase consistency.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.