ArticleNeuroImage2021
A large-scale structural and functional connectome of social mentalizing.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Relating Cognition to both Brain Structure and Function: A Systematic Review of Methods.Brain connectivity · 2023Pooled it
- Article
- Myelin, white matter, and social deficits in autism spectrum disorder.Neural regeneration research · 2026Article
- Brain neuromarkers predict self- and other-related mentalizing across adult, clinical, and developmental samples.Nature communications · 2026Article
- Human brain network for reading the mind from the eyes: beyond activated and deactivated regions.Social cognitive and affective neuroscience · 2026Article
- Evolving brain function and connectivity patterns during mentalizing in children and adults.Communications biology · 2026Article
- Neural correlates of risky monetary decision-making impacting others.Frontiers in human neuroscience · 2026Article
- From social cognition to consumption: toward an EEG-based approach to consumer mentalizing.Frontiers in psychology · 2026Article
- White matter disconnection in acquired criminality.Molecular psychiatry · 2025Article
- Crus control: effective cerebello-cerebral connectivity during social action prediction using dynamic causal modelling.Social cognitive and affective neuroscience · 2025Article
- Cortical areas associated to higher cognition drove primate brain evolution.Communications biology · 2025Article
- Minding the moving self: the centrality of body movement in the neurodynamics of the self and psychotherapeutic implications.Frontiers in psychiatry · 2025Review
- Sophisticated perspective-takers are distinctive: Neural idiosyncrasy of functional connectivity in the mentalizing network.iScience · 2024Article
- Animacy Processing in Autism: Event-Related Potentials Reflect Social Functioning Skills.Brain sciences · 2023Article
- A social-semantic working-memory account for two canonical language areas.Nature human behaviour · 2023Article
- Neural mechanisms underlying interindividual differences in intergenerational sustainable behavior.Scientific reports · 2023Article
- Every individual makes a difference: A trinity derived from linking individual brain morphometry, connectivity and mentalising ability.Human brain mapping · 2023Article
- Functional Segregation of the Human Cerebellum in Social Cognitive Tasks Revealed by TMS.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Mind your step: social cerebellum in interactive navigation.Social cognitive and affective neuroscience · 2023Article
- Effective cerebello-cerebral connectivity during implicit and explicit social belief sequence learning using dynamic causal modeling.Social cognitive and affective neuroscience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Humans have a remarkable ability to infer the mind of others. This mentalizing skill relies on a distributed network of brain regions but how these regions connect and interact is not well understood. Here we leveraged large-scale multimodal neuroimaging data to elucidate the brain-wide organization and mechanisms of mentalizing processing. Key connectomic features of the mentalizing network (MTN) have been delineated in exquisite detail. We found the structural architecture of MTN is organized by two parallel subsystems and constructed redundantly by local and long-range white matter fibers. We uncovered an intrinsic functional architecture that is synchronized according to the degree of mentalizing, and its hierarchy reflects the inherent information integration order. We also examined the correspondence between the structural and functional connectivity in the network and revealed their differences in network topology, individual variance, spatial specificity, and functional specificity. Finally, we scrutinized the connectome resemblance between the default mode network and MTN and elaborated their inherent differences in dynamic patterns, laterality, and homogeneity. Overall, our study demonstrates that mentalizing processing unfolds across functionally heterogeneous regions with highly structured fiber tracts and unique hierarchical functional architecture, which make it distinguishable from the default mode network and other vicinity brain networks supporting autobiographical memory, semantic memory, self-referential, moral reasoning, and mental time travel.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.