Evidence map›Paper›PMID 33933561›Full record

ArticleInsect biochemistry and molecular biology2021

Ammonium transporter AcAmt mutagenesis uncovers reproductive and physiological defects without impacting olfactory responses to ammonia in the malaria vector mosquito Anopheles coluzzii.

Zi Ye, Feng Liu, Stephen T Ferguson, Adam Baker, R Jason Pitts, Laurence J Zwiebel

Open access · greenAbstract read
In one paragraph

Article in Insect biochemistry and molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Discrete roles of Ir76b ionotropic coreceptor impact olfaction, blood feeding, and mating in the malaria vector mosquitoProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Review
  7. Olfaction in Anopheles mosquitoes.Chemical senses · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zi YeDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
Feng LiuDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
Stephen T FergusonDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
Adam BakerDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA.
R Jason PittsDepartment of Biology, Baylor University, Waco, TX, 76706, USA.
Laurence J ZwiebelDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA. Electronic address: l.zwiebel@vanderbilt.edu.
Vanderbilt University · USBaylor University · US

Funding

Molecular Characterization of an Anopheline Ammonium TransporterR21AI113960 · NIAID · VANDERBILT UNIVERSITY · PI ZWIEBEL, LAURENCE J · 2016 to 2017
$432k
NIAID NIH HHS R21 AI113960
6 · The paper itself

Abstract

Anopheline mosquitoes are the sole vectors of malaria and rely on olfactory cues for host seeking in which ammonia derived from human sweat plays an essential role. To investigate the function of the Anopheles coluzzii ammonium transporter (AcAmt) in the mosquito olfactory system, we generated an AcAmt null mutant line using CRISPR/Cas9. AcAmt

Indexed as

AnophelesAmmoniaAmmonium CompoundsAnimalsCation Transport ProteinsInsect ProteinsLarvaMalariaMosquito VectorsMutagenesisOdorantsReproductionSensillaSmellAmmoniaAmmonium CompoundsCation Transport ProteinsInsect ProteinsAmmonium transporterAnopheles coluzziiCoeloconic sensillaCRISPR/Cas9Mosquito reproductionOlfaction

Identifiers

PMID33933561
PMCPMC8187335
OpenAlexW3157779908

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.