ArticleThe Journal of infection2021
Seroprevalence of SARS-CoV-2 antibodies in university students: Cross-sectional study, December 2020, England.
Article in The Journal of infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Trial
- Evaluation of independent self-collected blood specimens for COVID-19 antibody detection among the US veteran population.Diagnostic microbiology and infectious disease · 2022Trial
- Factors influencing the time to COVID-19 antigen tests negative conversion among students at a Chinese university: a retrospective analysis.BMC infectious diseases · 2024Article
- Serological survey in a university community after the fourth wave of COVID-19 in Senegal.PloS one · 2024Article
- Seroprevalence of SARS-CoV-2 antibodies and associated risk factors during the second wave of infection in a university community in Cameroon.Influenza and other respiratory viruses · 2023Article
- Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults.Communications medicine · 2023Article
- Article
- Optimizing the implementation of a participant-collected, mail-based SARS-CoV-2 serological survey in university-affiliated populations: lessons learned and practical guidance.BMC public health · 2022Article
- Nucleocapsid and spike antibody responses following virologically confirmed SARS-CoV-2 infection: an observational analysis in the Virus Watch community cohort.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Observational
- Article
- Comparison of a Blood Self-Collection System with Routine Phlebotomy for SARS-CoV-2 Antibody Testing.Diagnostics (Basel, Switzerland) · 2022Article
- Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning.Scientific reports · 2022Article
- Effect of Returning University Students on COVID-19 Infections in England, 2020.Emerging infectious diseases · 2022Article
- A Cross-Sectional Study of Exposure Factors Associated with Seropositivity for SARS-CoV-2 Antibodies during the Second Epidemic Wave among a Sample of the University of Corsica (France).International journal of environmental research and public health · 2022Article
- Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission.Nature communications · 2022Article
- At-home blood collection and stabilization in high temperature climates usingFrontiers in digital health · 2022Article
- Assessing the use of a micro-sampling device for measuring blood protein levels in healthy subjects and COVID-19 patients.PloS one · 2022Article
- Characterization of IgG Antibody Response against SARS-CoV-2 (COVID-19) in the Cypriot Population.Microorganisms · 2021Article
- High COVID-19 transmission potential associated with re-opening universities can be mitigated with layered interventions.Nature communications · 2021Article
- Prevalence of SARS-CoV-2 Infection at the University of Barcelona during the Third COVID-19 Pandemic Wave in Spain.International journal of environmental research and public health · 2021Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn England, the reopening of universities in September 2020 coincided with a rapid increase in SARS-CoV-2 infection rates in university aged young adults. This study aimed to estimate SARS-CoV-2 antibody prevalence in students attending universities that had experienced a COVID-19 outbreak after reopening for the autumn term in September 2020.
methodsA cross-sectional serosurvey was conducted during 02-11 December 2020 in students aged ≤ 25 years across five universities in England. Blood samples for SARS-CoV-2 antibody testing were obtained using a self-sampling kit and analysed using the Abbott SARS-CoV-2 N antibody and/or an in-house receptor binding domain (RBD) assay.
findingsSARS-CoV-2 seroprevalence in 2,905 university students was 17.8% (95%CI, 16.5-19.3), ranging between 7.6%-29.7% across the five universities. Seropositivity was associated with being younger likely to represent first year undergraduates (aOR 3.2, 95% CI 2.0-4.9), living in halls of residence (aOR 2.1, 95% CI 1.7-2.7) and sharing a kitchen with an increasing number of students (shared with 4-7 individuals, aOR 1.43, 95%CI 1.12-1.82; shared with 8 or more individuals, aOR 1.53, 95% CI 1.04-2.24). Seropositivity was 49% in students living in halls of residence that reported high SARS-CoV-2 infection rates (>8%) during the autumn term.
interpretationDespite large numbers of cases and outbreaks in universities, less than one in five students (17.8%) overall had SARS-CoV-2 antibodies at the end of the autumn term in England. In university halls of residence affected by a COVID-19 outbreak, however, nearly half the resident students became infected and developed SARS-CoV-2 antibodies.
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