Evidence map›Paper›PMID 33933091›Full record

ArticleHealth and quality of life outcomes2021

Resilience and pain catastrophizing among patients with total knee arthroplasty: a cohort study to examine psychological constructs as predictors of post-operative outcomes.

Vesta C Nwankwo, William A Jiranek, Cynthia L Green, Kelli D Allen, Steven Z George, Janet Prvu Bettger

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Health and quality of life outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05461092 early_phase1recruitingnot on this mapstarted 2024, after this paper: background citation

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

TypeinterventionalSponsorUniversity of IowaRan2024 to 2026Enrolled50ConditionsDelirium, Pain, Back, Spinal Fusion, Thoracolumbar Interfascial Plane BlockArmsThoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Blood Test, 3D CAM Delirium Severity Scoring, Generalized Anxiety Disorder 7-item (GAD-7) scale, Numerical Rating Score (NRS)
NCT07609056 active not recruitingnot on this mapstarted 2026, after this paper: background citation

The Role of Rumination and Worry in Pain and Functional Limitation in Patients With Knee Osteoarthritis: A Cross-Sectional Study Considering Radiographic Severity

TypeobservationalSponsorFatih Sultan Mehmet Training and Research HospitalRan2026 to 2026Enrolled103ConditionsOsteo Arthritis Knee, Worries, Pain or Disability, Rumination
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vesta C NwankwoDuke University School of Medicine, Durham, NC, USA. vcn5@duke.edu.ORCID http://orcid.org/0000-0002-0380-4616
William A JiranekDepartment of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Cynthia L GreenDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Kelli D AllenCenter to Accelerate Discovery and Practice Transformation, Durham VA Health Care System, Durham, NC, USA.
Steven Z GeorgeDepartment of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Janet Prvu BettgerDepartment of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Duke University · USUniversity of North Carolina at Chapel Hill · US

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
NCATS NIH HHS UL1 TR002553NCATS NIH HHS UL1TR002553
6 · The paper itself

Abstract

backgroundPatients' psychological health may influence recovery and functional outcomes after total knee arthroplasty (TKA). Pain catastrophizing, known to be associated with poor function following TKA, encompasses rumination, magnification, and helplessness that patients feel toward their pain. Resilience, however, is an individual's ability to adapt to adversity and may be an important psychological construct that supersedes the relationship between pain catastrophizing and recovery. In this study we sought to identify whether pre-operative resilience is predictive of 3-month postoperative outcomes after adjusting for pain catastrophizing and other covariates.

methodsPatients undergoing TKA between January 2019 and November 2019 were included in this longitudinal cohort study. Demographics and questionnaires [Brief Resilience Scale (BRS), Pain Catastrophizing Scale (PCS), Knee injury and Osteoarthritis Outcome Score, Junior (KOOS, JR.) and Patient-Reported Outcomes Measurement Information System Physical and Mental Health (PROMIS PH and MH, respectively)] were collected preoperatively and 3 months postoperatively. Multivariable regression was used to test associations of preoperative BRS with postoperative outcomes, adjusting for PCS and other patient-level sociodemographic and clinical characteristics.

resultsThe study cohort included 117 patients with a median age of 67.0 years (Q1-Q3: 59.0-72.0). Fifty-three percent of patients were women and 70.1% were white. Unadjusted analyses identified an association between resilience and post-operative outcomes and the relationship persisted for physical function after adjusting for PCS and other covariates; in multivariable linear regression analyses, higher baseline resilience was positively associated with better postoperative knee function (β = 0.24, p = 0.019) and better general physical health (β = 0.24, p = 0.013) but not general mental health (β = 0.04, p = 0.738).

conclusionsOur prospective cohort study suggests that resilience predicts postoperative knee function and general physical health in patients undergoing TKA. Exploring interventions that address preoperative mental health and resilience more specifically may improve self-reported physical function outcomes of patients undergoing TKA.

Indexed as

Resilience, PsychologicalAgedArthroplasty, Replacement, KneeCatastrophizationFemaleHumansLongitudinal StudiesMaleMiddle AgedPostoperative PainPostoperative PeriodProspective StudiesQuality of LifeSurveys and QuestionnairesArthroplasty knee resilience pain catastrophizing function physical mental health outcomes

Identifiers

PMID33933091
PMCPMC8088639
OpenAlexW3158489183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.