Evidence map›Paper›PMID 33933045›Full record

ArticleBMC public health2021

An ecological study of chronic kidney disease in five Mesoamerican countries: associations with crop and heat.

Erik Hansson, Ali Mansourian, Mahdi Farnaghi, Max Petzold, Kristina Jakobsson

Abstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Observational
  11. Climate change and nephrology.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
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  16. Workplace Intervention for Heat Stress: Essential Elements of Design, Implementation, and Assessment.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erik HanssonSchool of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden. erik.hansson@amm.gu.se.ORCID http://orcid.org/0000-0002-9779-6820
Ali MansourianGIS Centre, Department of Physical Geography and Ecosystem Science, Lund University, Lund, Sweden.
Mahdi FarnaghiGIS Centre, Department of Physical Geography and Ecosystem Science, Lund University, Lund, Sweden.
Max PetzoldSchool of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Kristina JakobssonSchool of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

Funding

Forskningsrådet om Hälsa, Arbetsliv och Välfärd 2019-01548Vetenskapsrådet 2017-5426
6 · The paper itself

Abstract

backgroundMesoamerica is severely affected by an epidemic of Chronic Kidney Disease of non-traditional origin (CKDnt), an epidemic with a marked variation within countries. We sought to describe the spatial distribution of CKDnt in Mesoamerica and examine area-level crop and climate risk factors.

methodsCKD mortality or hospital admissions data was available for five countries: Mexico, Guatemala, El Salvador, Nicaragua and Costa Rica and linked to demographic, crop and climate data. Maps were developed using Bayesian spatial regression models. Regression models were used to analyze the association between area-level CKD burden and heat and cultivation of four crops: sugarcane, banana, rice and coffee.

resultsThere are regions within each of the five countries with elevated CKD burden. Municipalities in hot areas and much sugarcane cultivation had higher CKD burden, both compared to equally hot municipalities with lower intensity of sugarcane cultivation and to less hot areas with equally intense sugarcane cultivation, but associations with other crops at different intensity and heat levels were not consistent across countries.

conclusionMapping routinely collected, already available data could be a first step to identify areas with high CKD burden. The finding of higher CKD burden in hot regions with intense sugarcane cultivation which was repeated in all five countries agree with individual-level studies identifying heavy physical labor in heat as a key CKDnt risk factor. In contrast, no associations between CKD burden and other crops were observed.

Indexed as

Hot TemperatureRenal Insufficiency, ChronicBayes TheoremCosta RicaEl SalvadorGuatemalaHumansMexicoNicaraguaAgricultureChronic kidney disease (CKD)Chronic kidney disease of non-traditional origin (CKDnt)Chronic kidney disease of uncertain etiology (CKDu)Heat stressMesoamerican nephropathy (MeN)Occupation

Identifiers

PMID33933045
PMCPMC8088703

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.