Evidence map›Paper›PMID 33932822›Full record

ArticleResearch in veterinary science2021

Virucidal and antiviral effects of Thymus vulgaris essential oil on feline coronavirus.

Cristiana Catella, Michele Camero, Maria Stella Lucente, Giuseppe Fracchiolla, Sabina Sblano, Maria Tempesta, Vito Martella, Canio Buonavoglia, Gianvito Lanave

Open access · greenAbstract read
In one paragraph

Article in Research in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Antiviral Efficacy ofLife (Basel, Switzerland) · 2024
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  11. Review
  12. Review
  13. Assessing Contact Time and Concentration ofAntibiotics (Basel, Switzerland) · 2023
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  14. Pilot Study on the Action ofAntibiotics (Basel, Switzerland) · 2023
    Article
  15. Article
  16. In Vitro Antiviral Evaluations of ColdmixCurrent issues in molecular biology · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cristiana CatellaDepartment of Veterinary Medicine, University of Aldo Moro of Bari, Valenzano, Italy.
Michele CameroDepartment of Veterinary Medicine, University of Aldo Moro of Bari, Valenzano, Italy.
Maria Stella LucenteDepartment of Veterinary Medicine, University of Aldo Moro of Bari, Valenzano, Italy.
Giuseppe FracchiollaDepartment of Pharmacy-Drug Sciences, University of Aldo Moro of Bari, Bari, Italy.
Sabina SblanoDepartment of Pharmacy-Drug Sciences, University of Aldo Moro of Bari, Bari, Italy.
Maria TempestaDepartment of Veterinary Medicine, University of Aldo Moro of Bari, Valenzano, Italy.
Vito MartellaDepartment of Veterinary Medicine, University of Aldo Moro of Bari, Valenzano, Italy.
Canio BuonavogliaDepartment of Veterinary Medicine, University of Aldo Moro of Bari, Valenzano, Italy.
Gianvito LanaveDepartment of Veterinary Medicine, University of Aldo Moro of Bari, Valenzano, Italy. Electronic address: gianvito.lanave@uniba.it.
University of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline infectious peritonitis (FIP) is a fatal systemic disease of felids caused by a Coronavirus (CoV) (FIPV). In spite of its clinical relevance and impact on feline health, currently the therapeutic possibilities for treatment of FIP in cats are limited. The emergence of the pandemic Severe Respiratory Syndrome (SARS) coronavirus (CoV) type 2 (SARS-CoV-2), etiological agent of the 2019 Coronavirus Disease (COVID-19), able to infect a broad spectrum of animal species including cats, triggered the interest for the development of novel molecules with antiviral activity for treatment of CoV infections in humans and animals. Essential oils (EOs) have raised significant attention for their antiviral properties integrating and, in some cases, replacing conventional drugs. Thymus vulgaris EO (TEO) has been previously shown to be effective against several RNA viruses including CoVs. In the present study the antiviral efficacy of TEO against FIPV was evaluated in vitro. TEO at 27 μg/ml was able to inhibit virus replication with a significant reduction of 2 log10 TCID

Indexed as

AnimalsCatsCell LineCoronavirus, FelineHumansOils, VolatilePlant OilsThymus PlantVirus ReplicationOils, VolatilePlant OilsFeline CoronavirusFIPThymus Essential OilThymus vulgaris

Identifiers

PMID33932822
PMCPMC8061179
OpenAlexW3158389035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.