Evidence map›Paper›PMID 33932623›Full record

ReviewCurrent opinion in cell biology2021

Regulation and physiology of membrane contact sites.

Rossella Venditti, Cathal Wilson, Maria Antonietta De Matteis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current opinion in cell biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Organelle Communication with the Nucleus.Results and problems in cell differentiation · 2024
    Review
  9. Review
  10. Phosphoinositide transport and metabolism at membrane contact sites.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2022
    Review
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rossella VendittiTelethon Institute of Genetics and Medicine, Pozzuoli, Italy; Department of Molecular Medicine and Medical Biotechnology, University of Napoli Federico II-Medical School, Naples, Italy.
Cathal WilsonTelethon Institute of Genetics and Medicine, Pozzuoli, Italy.
Maria Antonietta De MatteisTelethon Institute of Genetics and Medicine, Pozzuoli, Italy; Department of Molecular Medicine and Medical Biotechnology, University of Napoli Federico II-Medical School, Naples, Italy. Electronic address: dematteis@tigem.it.
Telethon Institute Of Genetics And Medicine · IT

Funding

European Research Council 670881
6 · The paper itself

Abstract

Membrane contact sites (MCSs) in addition to impacting the functions of membrane-limited organelles also have a role in the spatial and functional organization of cells, tissues and whole organisms. MCSs have been identified between all organelles and the identification of their molecular composition has progressed significantly in recent years. Equally important is how MCSs respond dynamically to physiological stimuli, how this is regulated, and the physiological roles of MCSs in tissues and at the organismal level, an area that still remains relatively unexplored. In the present review, we focus on the regulation of MCSs, considerations of their function at the organismal level, and how mutations of MCS components linked to genetic diseases might inform us about their physiological relevance.

Indexed as

Endoplasmic ReticulumMitochondrial MembranesCell Membrane

Identifiers

PMID33932623
OpenAlexW3157118992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.