Evidence map›Paper›PMID 33932309›Full record

ArticleInternational journal of clinical practice2021

Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is influenced by the type of transport medium: Implications for diagnosis and monitoring.

Nikhil Patkar, Sweta Rajpal, Nitin Shetty, Anant Gokarn, Sumeet Mirgh, Shesheer Munipally, Sudhir Nair, Amit Joshi, Vedang Murthy, Navin Khattry and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Nikhil PatkarACTREC, Navi Mumbai, India.ORCID https://orcid.org/0000-0001-9234-2857
Sweta RajpalACTREC, Navi Mumbai, India.
Nitin ShettyACTREC, Navi Mumbai, India.
Anant GokarnACTREC, Navi Mumbai, India.
Sumeet MirghACTREC, Navi Mumbai, India.
Shesheer MunipallyACTREC, Navi Mumbai, India.
Sudhir NairACTREC, Navi Mumbai, India.
Amit JoshiACTREC, Navi Mumbai, India.
Vedang MurthyACTREC, Navi Mumbai, India.
Navin KhattryACTREC, Navi Mumbai, India.
Sudeep GuptaACTREC, Navi Mumbai, India.
Advanced Centre for Treatment, Research and Education in Cancer · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is unclear if the use of a molecular transport medium (MTM) containing guanidine isothiocyanate (GITC) would be advantageous over the CDC recommended, commonly used viral transport medium (VTM). We retested 70 SARS-CoV2 cases by RT-PCR in varying stages of follow-up using MTM and VTM in parallel and found discrepant results of RNase P, E and N genes. Majority (81%) patients tested positive with MTM as compared with VTM (27.1%). Even patients who were sampled 3 weeks after diagnosis demonstrated a significant discrepancy in the positivity rates between MTM vs VTM raising concerns about the clinical utility of VTM.

Indexed as

COVID-19SARS-CoV-2Clinical Laboratory TechniquesCOVID-19 TestingHumansRNA, ViralRNA, Viral

Identifiers

PMID33932309
PMCPMC8236963
OpenAlexW3159442102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.