Evidence map›Paper›PMID 33931803›Full record

ReviewReviews in endocrine & metabolic disorders2021

Physical activity and adipokine levels in individuals with type 2 diabetes: A literature review and practical applications.

Hassane Zouhal, Navabeh Zare-Kookandeh, Marjan Mosalman Haghighi, Ali Daraei, Maysa de Sousa, Mohammad Soltani, Abderraouf Ben Abderrahman, Jed M Tijani, Anthony C Hackney, Ismail Laher and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  11. Biomarkers of Arginine Methylation in Diabetic Nephropathy: Novel Insights from Bioinformatics Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hassane ZouhalM2S (Laboratoire Mouvement, University of Rennes, 1274, F-35000, Sport, Santé), France. hassane.zouhal@univ-rennes2.fr.ORCID 0000-0001-6743-6464
Navabeh Zare-Kookandeh *Institute for Health and Sport, Victoria University, Melbourne, Australia.ORCID 0000-0002-5500-7328
Marjan Mosalman Haghighi *Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.ORCID 0000-0003-3481-1517
Ali DaraeiDepartment of Biological Sciences in Sport, Faculty of Sports Sciences and Health, Shahid Beheshti University, Tehran, Iran.ORCID 0000-0002-7639-9690
Maysa de SousaUniversity of Sao Paolo, Sao Paolo, Brazil.ORCID 0000-0003-2211-2209
Mohammad SoltaniDepartment of Biological Sciences in Sport, Faculty of Sports Sciences and Health, Shahid Beheshti University, Tehran, Iran.ORCID 0000-0002-8659-9477
Abderraouf Ben AbderrahmanISSEP, University of La Manouba, Tunis, Tunisia.ORCID 0000-0003-1351-8717
Jed M TijaniISSEP, University of La Manouba, Tunis, Tunisia.ORCID 0000-0001-8889-3816
Anthony C HackneyDepartment of Exercise & Sport Science, Department of Nutrition, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0002-6607-1472
Ismail LaherFaculty of Medicine, Department of Anesthesiology, The University of British Columbia, Pharmacology & Therapeutics, Vancouver, Canada.ORCID 0000-0002-3917-4417
Ayoub SaeidiDepartment of Physical Education and Sport Sciences, University of Kurdistan, Sanandaj, Iran. saeidi_as68@yahoo.com.ORCID 0000-0003-2458-6256

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We review the effects of acute and long-term physical activity on adipokine levels in individuals with type 2 diabetes (T2D). Three electronic databases were searched. Studies made in animal models were excluded, while studies based on participants with and without T2D, and also studies with type 1 diabetes were included. Of the 2,450 citations, 63 trials, including randomised control trials, cross-sectional and longitudinal studies, met our inclusion criteria. Seventy and five percent of studies reported the effects of physical activity on tumor necrosis factor-alpha (TNFα), interleukin 6 (IL-6), adiponectin, visfatin, omentin-1, and leptin levels. There are no robust results due to variations in exercise modality, intensity, duration, and also differences in cohort characteristics in the literature. Only four studies described the effects of an acute session of physical activity on adipokine levels. Overall, physical activity improves diabetes status by regulating adipokine levels. However, long-term aerobic + resistance training combined with dietary modifications is likely to be a more effective strategy for improving adipokines profiles in patients with type 2 diabetes.

Indexed as

AdipokinesDiabetes Mellitus, Type 2AdiponectinCross-Sectional StudiesExerciseHumansLeptinAdipokinesAdiponectinLeptinAcuteCytokinesDiabetesInflammationLong-term physical activityPhysical activity

Identifiers

PMID33931803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.