Evidence map›Paper›PMID 33931733›Full record

ArticleMolecular psychiatry2021

Cannabinoid receptor activation acutely increases synaptic vesicle numbers by activating synapsins in human synapses.

Christopher Patzke, Jinye Dai, Marisa M Brockmann, Zijun Sun, Pascal Fenske, Christian Rosenmund, Thomas C Südhof

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. The Role of Cannabis in the Development of Psychosis.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2024
    Review
  10. Article
  11. Article
  12. A Simple CaMethods in molecular biology (Clifton, N.J.) · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Frontiers in neuroscience · 2022
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Christopher Patzke *Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA. cpatzke@nd.edu.ORCID http://orcid.org/0000-0001-7293-8936
Jinye Dai *Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA.ORCID http://orcid.org/0000-0002-8497-3154
Marisa M Brockmann *Institute of Neurophysiology, Charité Universitätsmedizin, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-1386-5359
Zijun SunDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA.ORCID http://orcid.org/0000-0001-5386-5495
Pascal FenskeInstitute of Neurophysiology, Charité Universitätsmedizin, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0003-4709-8984
Christian RosenmundInstitute of Neurophysiology, Charité Universitätsmedizin, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-3905-2444
Thomas C SüdhofDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA.
Charité - Universitätsmedizin Berlin · DEHoward Hughes Medical Institute · USStanford University · USUniversity of Notre Dame · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabis and cannabinoid drugs are central agents that are used widely recreationally and are employed broadly for treating psychiatric conditions. Cannabinoids primarily act by stimulating presynaptic CB1 receptors (CB1Rs), the most abundant G-protein-coupled receptors in brain. CB1R activation decreases neurotransmitter release by inhibiting presynaptic Ca

Indexed as

CannabinoidsSynapsinsAnimalsHumansMiceReceptors, CannabinoidSynapsesSynaptic TransmissionSynaptic VesiclesCannabinoidsReceptors, CannabinoidSynapsins

Identifiers

PMID33931733
OpenAlexW3159022530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.