Evidence map›Paper›PMID 33931455›Full record

ArticleScience advances2021

A skin-conformable wireless sensor to objectively quantify symptoms of pruritus.

Keum San Chun, Youn J Kang, Jong Yoon Lee, Morgan Nguyen, Brad Lee, Rachel Lee, Han Heul Jo, Emily Allen, Hope Chen, Jungwoo Kim and 14 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 6 institutions in 1 country.

Keum San ChunElectrical and Computer Engineering, The University of Texas at Austin, Austin, TX 78712, USA.ORCID 0000-0001-5695-5816
Youn J KangQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-8433-5515
Jong Yoon LeeQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0003-1626-7669
Morgan NguyenNorthwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Brad LeeNorthwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Rachel LeeSibel Health, Niles, IL 60714, USA.
Han Heul JoSibel Health, Niles, IL 60714, USA.ORCID 0000-0002-4351-5886
Emily AllenDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0003-1982-1901
Hope ChenCenter for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-5751-8124
Jungwoo KimSibel Health, Niles, IL 60714, USA.
Lian YuElectrical and Computer Engineering, University of Illinois at Champaign-Urbana, Champaign, IL 61801, USA.ORCID 0000-0003-3771-7980
Xiaoyue NiQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-1822-1122
KunHyuck LeeQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.
Hyoyoung JeongQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-1808-7824
JooHee LeeSibel Health, Niles, IL 60714, USA.
Yoonseok ParkQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-1702-0986
Ha Uk ChungQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0003-3592-8944
Alvin W LiDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0003-2591-838X
Peter A LioChicago Eczema Center, Chicago, IL 60654, USA.ORCID 0000-0001-7600-0152
Albert F YangDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Anna B FishbeinDepartment of Pediatrics (Allergy and Immunology), Ann & Robert H. Lurie Children's Hospital, Chicago, IL 60611, USA.
Amy S PallerCenter for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0001-6187-6549
John A RogersQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA. jrogers@northwestern.edu stevexu@northwestern.edu.ORCID 0000-0002-3830-5980
Shuai XuQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA. jrogers@northwestern.edu stevexu@northwestern.edu.ORCID 0000-0003-3560-6945
Northwestern University · USSibel (United States) · USAssociation House of Chicago · USLurie Children's Hospital · USThe University of Texas at Austin · USUniversity of Illinois Urbana-Champaign · US

Funding

Circadian Rhythms of Skin Barrier, Pruritus and Inflammation in Atopic DermatitisK23AR075108 · NIAMS · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI FISHBEIN, ANNA B · 2019 to 2022
$674k
Novel Wearable and Wireless Scratch Sensor as a Drug Discovery ToolU01FD007001 · FDA · SONICA, LLC · PI XU, NING · 2020 to 2020
$249k
FDA HHS U01 FD007001NIAMS NIH HHS K23 AR075108
6 · The paper itself

Abstract

Itch is a common clinical symptom and major driver of disease-related morbidity across a wide range of medical conditions. A substantial unmet need is for objective, accurate measurements of itch. In this article, we present a noninvasive technology to objectively quantify scratching behavior via a soft, flexible, and wireless sensor that captures the acousto-mechanic signatures of scratching from the dorsum of the hand. A machine learning algorithm validated on data collected from healthy subjects (

Identifiers

PMID33931455
PMCPMC8087407
OpenAlexW3157301788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.