Evidence map›Paper›PMID 33931286›Full record

ArticleUltrasound in medicine & biology2021

Automated Segmentation of the Median Nerve in the Carpal Tunnel using U-Net.

Raymond T Festen, Verena J M M Schrier, Peter C Amadio

Abstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raymond T FestenDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Verena J M M SchrierDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Plastic, Reconstructive and Hand Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.
Peter C AmadioDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA. Electronic address: pamadio@mayo.edu.

Funding

Dynamic Ultrasound to Enhance Understanding of Carpal Tunnel SyndromeR01AR062613 · NIAMS · MAYO CLINIC ROCHESTER · PI AMADIO, PETER C. · 2014 to 2018
$1.7M
NIAMS NIH HHS R01 AR062613
6 · The paper itself

Abstract

Nerve area and motion in carpal tunnel syndrome (CTS) are currently under investigation in terms of prognostic potential. Therefore, there is increasing interest in non-invasive measurement of the nerve using ultrasound. Manual segmentation is time consuming and subject to inter-rater variation, providing an opportunity for automation. Dynamic ultrasound images (n = 5560) of carpal tunnels from 99 clinically diagnosed CTS patients were used to train a U-Net-shaped neural network. The best results from the U-Net were achieved with a location primer as initial region of interest for the segmentations during finger flexion (Dice coefficient = 0.88). This is comparable to the manual Dice measure of 0.92 and higher than the resulting automated Dice measure of wrist flexion (0.81). Although there is a dependency on image quality, a trained U-Net can reliably be used in the assessment of ultrasound-acquired median nerve size and mobility, considerably decreasing manual effort.

Indexed as

Neural Networks, ComputerCarpal Tunnel SyndromeHumansMedian NerveRange of Motion, ArticularUltrasonographyWrist JointCarpal tunnelMedian nerveSegmentationUltrasoundU-Net

Identifiers

PMID33931286
PMCPMC8169596

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.