Evidence map›Paper›PMID 33931226›Full record

ArticleKidney international2021

Immune response to SARS-CoV-2 infection and vaccination in patients receiving kidney replacement therapy.

T Alp Ikizler, P Toby Coates, Brad H Rovin, Pierre Ronco

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Kidney international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05057936 (Antibody Response After COVID-19 Vaccination in Chronic Kidney Disease and Kidney Transplant Patients), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05057936 completednot on this map

Antibody Response After COVID-19 Vaccination in Chronic Kidney Disease and Kidney Transplant Patients

TypeobservationalSponsorBangkok Metropolitan Administration Medical College and Vajira HospitalRan2021 to 2021Enrolled140ConditionsCovid19, Breakthrough Infection, CKD, Kidney TransplantArmsCOVID vaccine
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

T Alp IkizlerDepartment of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee, USA. Electronic address: alp.ikizler@vumc.org.
P Toby CoatesCentre for Clinical and Experimental Transplantation, The University of Adelaide, Adelaide, Australia.
Brad H RovinInternal Medicine-Nephrology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Pierre RoncoUnité Mixte de Recherche S 1155, Sorbonne Université, Université Pierre et Marie Curie Paris 06 and Institut National de la Santé et de la Recherche Médicale, Paris, France; Division of Nephrology, Centre Hospitalier du Mans, Le Mans, France.
Sorbonne Université · FRThe Ohio State University Wexner Medical Center · USUniversity of Adelaide · AUVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Kidney International, the initial experience regarding the immunogenicity of prior coronavirus disease 2019 (COVID-19) infection and the response to the COVID-19 vaccines among patients on maintenance dialysis and kidney transplant recipients is summarized. Preliminary data suggest that there is durability of immune response after COVID-19 infection. Although immune response to the first dose of vaccine is less in infection-naïve patients than healthy individuals in both groups, after the second vaccine dose a significant portion of patients receiving maintenance dialysis develop robust antibody titers, whereas kidney transplant recipients show a less-strong immune response.

Indexed as

Kidney TransplantationRenal DialysisAgedCOVID-19COVID-19 VaccinesFemaleHumansImmunityMaleMiddle AgedOutcome and Process Assessment, Health CarePandemicsRenal Replacement TherapySARS-CoV-2VaccinationCOVID-19 Vaccines

Identifiers

PMID33931226
PMCPMC8055920
OpenAlexW3154963136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.