SynthesisOrphanet journal of rare diseases2021
A systematic review of case reports of hepatic actinomycosis.
Synthesis in Orphanet journal of rare diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Clinical presentations, diagnosis, management, and outcomes of renal mucormycosis: An overview of case reports.Frontiers in medicine · 2022Pooled it
- IgG4-Related Hepatic Disease Unmasking Hepatic Actinomycosis.Journal of clinical immunology · 2026Article
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- Article
- Concurrent Hepatic Abscess and Pleural Empyema due toCase reports in infectious diseases · 2026Article
- Case Report: A clinical case of postoperative podaponeurotic abscess caused byFrontiers in medicine · 2026Article
- Concomitant Autoimmune Liver Disease and Hepatic Actinomycosis: A Diagnostic Challenge-Brief Report and Review of the Literature.International journal of molecular sciences · 2025Review
- An actinomycosis infection resembling peritoneal dissemination of rectal cancer: a case report.Surgical case reports · 2024Article
- Actinomyces-infected bronchopulmonary sequestration: An uncommon pathogen in a rare anomaly.Clinical case reports · 2024Article
- Rheumatoid arthritis complicated with cervical actinomycosis and ureteral obstruction: A case report and literature review.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Review
- An overview of case reports and case series of pulmonary actinomycosis mimicking lung cancer: a scoping review.Frontiers in medicine · 2024Article
- Article
- Intrahepatic cholangiocarcinoma with a liver abscess due to hepatic actinomycosis.Surgical case reports · 2023Article
- A case of recurrent acute cholecystitis caused by Actinomyces odontolyticus, rare actinomycosis.BMC infectious diseases · 2022Article
- Multiomics Analysis Reveals the Impact of Microbiota on Host Metabolism in Hepatic Steatosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- A 60-Year Literature Review on Hepatic Actinomycosis.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatic Actinomycosis (HA) is one of the infections that causes disorders in patients when diagnosed untimely and inappropriately.
methodsCase reports on HA in patients published between 2000 and April 2020 were gathered by carrying out a structured search through PubMed/Medline.
resultsThrough a survey of the Medline database, 130 studies were identified and then, 64 cases with HA were included in the final analysis. Asia had the largest share of cases with 37.5% (24 reports), followed by Europe and the Americas. Affected patients were predominantly males (64%) and the overall mortality rate was 1% with only one male patient in his 50 s dying. Nearly all patients (92%) were immunocompetent. However, in four patients, the use of immunosuppressive medication led to depression of the immune system. Most of the patients (80%) experienced complications. In terms of the complications, the most frequent ones were previous history of abdominal surgery (32%) and foreign bodies in the abdominopelvic region (20%). Actinomyces israelii was the most common pathogen isolated from patients. Abdominal pain (66%), fever (62%), weight loss (48%), night sweat, malaise, and anorexia (14%) over about 3.1 months were the most frequently reported clinical symptoms. Extension to one or more surrounding organs was evident in 18 patients (28%). Histopathologic examination confirmed infection in 67% of the patients and samples obtained from liver puncture biopsy (32%) were most frequently used in diagnosis. Surgery or puncture drainage + anti-infection was the most common method to treat patients and penicillin, Amoxicillin, Doxycycline, and ampicillin were the most frequently used drugs to control infection.
conclusionHA should be considered in patients with a subacute or chronic inflammatory process of the liver. With accurate and timely diagnosis of infection, extensive surgery can be prevented.
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