ArticleLipids in health and disease2021
Influence of uric acid on the correlation between waist circumference and triglyceride glucose index: an analysis from CHARLS.
Article in Lipids in health and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 22 citations in OpenAlex.
- Association of an estimated glucose disposal rate-frailty index with incident cardiovascular events in two prospective cohorts.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Nutrition-related biomarkers of metabolic disorders among immigrants in Athens, Greece: a cross- sectional study.Journal of diabetes and metabolic disorders · 2025Article
- Reference interval of serum uric acid among healthy children and adolescents in Nanjing, China, and influencing factors.Annals of medicine · 2025Article
- Temporal relationship between serum uric acid and muscle strength: a cross-sectional and longitudinal study of middle-aged and older adults.Scientific reports · 2025Article
- A J-shaped association between weight-adjusted waist index and cardiovascular disease: a longitudinal study from the CHARLS database.BMC public health · 2025Article
- Dynapenic abdominal obesity and the risks of heart disease and all-cause mortality: a 7-year longitudinal study among middle-aged and older Chinese adults.BMC public health · 2025Article
- Associations of estimated glucose disposal rate with frailty progression: results from two prospective cohorts.Cardiovascular diabetology · 2025Article
- Joint association of estimated glucose disposal rate and body mass index with new-onset stroke.Frontiers in neurology · 2025Article
- Article
- Serum Uric Acid, Hypertriglyceridemia, and Carotid Plaques: A Sub-Analysis of the URic Acid Right for Heart Health (URRAH) Study.Metabolites · 2024Article
- The role of high fat diet on serum uric acid level among healthy male first degree relatives of type 2 diabetes mellitus.Scientific reports · 2023Article
- Uric acid relationships with lipid profile and adiposity indices: Impact of different hyperuricemic thresholds.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Triglyceride-glucose index level and variability and outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention: an observational cohort study.Lipids in health and disease · 2022Observational
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3 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWaist circumference (WC) and uric acid (UA) are significantly related. Still, their temporal sequence and how the sequence works on future risk of triglyceride glucose (TyG) are unknown, especially in the Chinese population.
methodsCross-lagged panel model was used to analyze the reciprocal, longitudinal relationships among a set of interrelated variables. The mediation model was constructed to test the effect of the relationship between WC and UA on TyG.
resultsA total of 5727 subjects were enrolled in our study population, of which 53.5% were women, and the mean age was 59.0 (standard deviation, 8.62) years. After adjusting for traditional confounding factors, the results showed that a higher level of baseline WC was significantly associated with a higher level of follow-up UA (β = 0.003, P = 0.031) and follow-up TyG (β = 0.003, P < 0.001);. Simultaneously, there was no statistical association between the level of baseline UA and the level of follow-up WC (β = - 0.009, P = 0.951). The mediation effects of UA on WC-TyG were estimated to be 18.1% in adults, and 36.2% in women.
conclusionsThe current study demonstrated that higher baseline level of WC probably preceded UA' level in general population. In addition, UA mediated the relationship of WC to TyG, especially in females. And the possible mechanism would require further clarification.
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