Evidence map›Paper›PMID 33930828›Full record

ArticleMedical image analysis2021

Multi-site MRI harmonization via attention-guided deep domain adaptation for brain disorder identification.

Hao Guan, Yunbi Liu, Erkun Yang, Pew-Thian Yap, Dinggang Shen, Mingxia Liu

Open access · greenAbstract read
In one paragraph

Article in Medical image analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 135 citations in OpenAlex.

  1. Causal graph neural networks for healthcare.Nature biomedical engineering · 2026
    Review
  2. Review
  3. Review
  4. A functional system-informed graph neural network framework to quantify interpretable brain dysfunction in ASD.Neural networks : the official journal of the International Neural Network Society · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Differential dementia detection from multimodal brain images in a real-world dataset.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Structural MRI Harmonization via Disentangled Latent Energy-Based Style Translation.Machine learning in medical imaging. MLMI (Workshop) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Hao GuanDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Yunbi LiuDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.
Erkun YangDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Pew-Thian YapDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Dinggang ShenDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Mingxia LiuDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: mxliu@med.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

Quantifying Brain Abnormality by Multimodality Neuroimage Analysis,R01AG041721 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, MINGXIA · 2012 to 2019
$3.0M
Analyzing Large-Scale Neuroimaging Data in Alzheimer's DiseaseRF1AG053867 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2016
$2.5M
2/2 Phenotype Predictors of Cognitive Outcomes in Geriatric DepressionR01MH108560 · NIMH · DUKE UNIVERSITY · PI POTTER, GUY GLENN · 2016 to 2020
$1.8M
Comprehensive MR Fingerprinting for Infants and Young Children at Risk for Developmental Delays.R01HD112923 · NICHD · DUKE UNIVERSITY · PI Dan Ma, DEANNE E WILSON-COSTELLO · 2024 to 2026
$1.7M
NIA NIH HHS R01 AG041721NIA NIH HHS RF1 AG053867NICHD NIH HHS R01 HD112923NIMH NIH HHS R01 MH108560
6 · The paper itself

Abstract

Structural magnetic resonance imaging (MRI) has shown great clinical and practical values in computer-aided brain disorder identification. Multi-site MRI data increase sample size and statistical power, but are susceptible to inter-site heterogeneity caused by different scanners, scanning protocols, and subject cohorts. Multi-site MRI harmonization (MMH) helps alleviate the inter-site difference for subsequent analysis. Some MMH methods performed at imaging level or feature extraction level are concise but lack robustness and flexibility to some extent. Even though several machine/deep learning-based methods have been proposed for MMH, some of them require a portion of labeled data in the to-be-analyzed target domain or ignore the potential contributions of different brain regions to the identification of brain disorders. In this work, we propose an attention-guided deep domain adaptation (AD

Indexed as

Brain DiseasesMagnetic Resonance ImagingAttentionBrainHumansMachine LearningAttentionBrain disorderDomain adaptationHarmonizationStructural MRI

Identifiers

PMID33930828
PMCPMC8184627
OpenAlexW3153445520

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.