ArticlePloS one2021
Quantitative evaluation of microvacuole formation in five intraocular lens models made of different hydrophobic materials.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Capsular bag performance of an aspheric hydrophobic IOL after conventional phacoemulsification or femtosecond laser-assisted cataract surgery: 12-month results of a randomized prospective study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Trial
- Randomized multicenter trial to assess posterior capsule opacification and glistenings in two hydrophobic acrylic intraocular lenses.Scientific reports · 2023Trial
- Clinical Outcomes of a Monofocal, Optimized, Aspheric, Hydrophobic Acrylic Intraocular Lens Implant.Clinical ophthalmology (Auckland, N.Z.) · 2023Trial
- Long-Term Clarity of High-Water-Content Hydrophobic Acrylic Intraocular Lens: A 3-Year Randomized Comparison with a Hydrophobic Lens of Similar Material and Design.Ophthalmology and therapy · 2025Article
- Article
- Altering chromatic aberration: how this latest trend in intraocular-lens design affects visual quality in pseudophakic patients.Eye and vision (London, England) · 2023Article
- Objective Classification of Glistening in Implanted Intraocular Lenses Using Optical Coherence Tomography: Proposal for a New Classification and Grading System.Journal of clinical medicine · 2023Article
- A new software for automated counting of glistenings in intraocular lensesInternational journal of ophthalmology · 2023Article
- Early Clinical Experience with a New Hydrophobic Acrylic Single-Piece Monofocal Intraocular Lens.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Refractive and Visual Outcomes of a Monofocal Non-Constant Aberration Aspheric Intraocular Lens.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Etiology, pathogenesis, and management of acute intraocular lens opacification: a systematic review.International journal of ophthalmology · 2022Review
- Comparative analysis of in vitro accelerated glistening formation in foldable hydrophobic intraocular lenses.International ophthalmology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this laboratory study, we assessed the resistance to microvacuole (glistening) formation in hydrophobic intraocular lenses (IOLs). Glistenings were induced in five lenses each of five different hydrophobic acrylic IOL models, using an established in vitro laboratory model: 800C (Rayner, Worthing, UK), AcrySof SN60WF (Alcon, Fort Worth, USA), Tecnis ZCB00 (Johnson & Johnson Vision, Santa Ana, USA), Vivinex XY1 (Hoya, Tokyo, Japan) and CT Lucia 611P (Zeiss, Oberkochen, Germany). We evaluated the number of microvacuoles per square millimeter (MV/mm2) in the central part of each IOL. Results were analyzed statistically, and mean glistening numbers were ranked, with the highest in the SN60WF which had 66.0 (±45.5) MVs/mm, followed by the 611P with 30.7 (±8.4) MVs/mm2. The 800C and XY1 showed comparable values of 2.0 (±3.6) and 2.7 (±2.4) MVs/mm2, respectively. ZCB00 had the lowest number with 0.9 (±0.6) MVs/mm2. This study shows that the resistance to glistening formation differs depending on the hydrophobic acrylic copolymer composition of the IOL material. Some IOLs from current clinical use are still prone to develop glistenings whereas others, including the ZCB00, 800C and XY1 show high resistance to microvacuole formation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.