Evidence map›Paper›PMID 33930082›Full record

ArticlePloS one2021

Maternal obesity and stillbirth at term; placental pathology-A case control study.

Hanna Åmark, Magnus Westgren, Meeli Sirotkina, Ingela Hulthén Varli, Martina Persson, Nikos Papadogiannakis

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hanna ÅmarkDept of Clinical Science and Education, Unit of Obstetrics and Gynecology, Karolinska Institute, Södersjukhuset, Stockholm, Sweden.ORCID 0000-0001-7599-567X
Magnus WestgrenDept of Clinical Sciences, Intervention & Technology, Karolinska Institute, Stockholm, Sweden.
Meeli SirotkinaDep of Laboratory Medicine, Karolinska University Hospital Huddinge, Huddinge, Sweden.
Ingela Hulthén VarliDepartment of Women´s and Children´s Health, Karolinska Institutet, Stockholm, Sweden.
Martina PerssonDep of Medicine, Clinical Epidemiology Unit, Karolinska University Hospital, Stockholm, Sweden.
Nikos PapadogiannakisDep of Laboratory Medicine, Karolinska University Hospital Huddinge, Huddinge, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim was to explore the potential role of the placenta for the risk of stillbirth at term in pregnancies of obese women.

methodsThis was a case-control study comparing placental findings from term stillbirths with placental findings from live born infants. Cases were singleton term stillbirths to normal weight or obese women, identified in the Stockholm stillbirth database, n = 264 and n = 87, respectively. Controls were term singletons born alive to normal weight or obese women, delivered between 2002-2005 and between 2018-2019. Placentas were compared between women with stillborn and live-born infants, using logistic regression analyses.

resultsA long and hyper coiled cord, cord thrombosis and velamentous cord insertion were stronger risk factors for stillbirth in obese women compared to normal weight women. When these variables were adjusted for in the logistic regression analysis, also adjusted for potential confounders, the odds ratio for stillbirth in obese women decreased from 1.89 (CI 1.24-2.89) to 1.63 (CI 1.04-2.56).

conclusionApproximately one fourth of the effect of obesity on the risk of stillbirth in term pregnancies is explained by umbilical cord associated pathology.

Indexed as

StillbirthAdultCase-Control StudiesDatabases, FactualFemaleHumansLive BirthPlacentaPregnancyPregnancy ComplicationsPregnancy in ObesityRisk FactorsUmbilical Cord

Identifiers

PMID33930082
PMCPMC8087010
OpenAlexW3159742121

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.