Evidence map›Paper›PMID 33929958›Full record

ArticleIEEE transactions on medical imaging2021

Assessing the Impact of Deep Neural Network-Based Image Denoising on Binary Signal Detection Tasks.

Kaiyan Li, Weimin Zhou, Hua Li, Mark A Anastasio

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Regression Is All You Need for Medical Image Translation.IEEE transactions on medical imaging · 2026
    Article
  3. Article
  4. Survey of Deep Learning and Physics-Based Approaches in Computational Wave Imaging.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kaiyan Li
Weimin Zhou
Hua Li
Mark A Anastasio

Funding

Safe, rapid & functional pediatric brain imaging using photoacoustic computed tomographyR01NS102213 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANASTASIO, MARK A, WANG, LIHONG · 2017 to 2021
$3.0M
AN ENABLING TECHNOLOGY FOR PRECLINICAL X-RAY IMAGING OF BIOMATERIALS IN-VIVOR01EB020604 · NIBIB · WASHINGTON UNIVERSITY · PI ANASTASIO, MARK A, BREY, ERIC M · 2016 to 2019
$2.3M
Multimodal Biomarkers For Oropharyngeal CancerR01CA233873 · NCI · WASHINGTON UNIVERSITY · PI LI, HUA · 2019 to 2024
$2.0M
DEVELOPMENT OF A RAPID METHOD FOR IMAGING REGIONAL VENTILATION IN SMALL ANIMALS W/O CONTRAST AGENTSR01EB023045 · NIBIB · WASHINGTON UNIVERSITY · PI ANASTASIO, MARK A · 2017 to 2020
$1.7M
RADIOMICS-BASED PROGNOSTIC MODEL OF CERVICAL CANCER HABITATSR21CA223799 · NCI · WASHINGTON UNIVERSITY · PI GRIGSBY, PERRY WAYNE, LI, HUA · 2018 to 2019
$368k
NCI NIH HHS R01 CA233873NCI NIH HHS R21 CA223799NIBIB NIH HHS R01 EB020604NIBIB NIH HHS R01 EB023045NINDS NIH HHS R01 NS102213
6 · The paper itself

Abstract

A variety of deep neural network (DNN)-based image denoising methods have been proposed for use with medical images. Traditional measures of image quality (IQ) have been employed to optimize and evaluate these methods. However, the objective evaluation of IQ for the DNN-based denoising methods remains largely lacking. In this work, we evaluate the performance of DNN-based denoising methods by use of task-based IQ measures. Specifically, binary signal detection tasks under signal-known-exactly (SKE) with background-known-statistically (BKS) conditions are considered. The performance of the ideal observer (IO) and common linear numerical observers are quantified and detection efficiencies are computed to assess the impact of the denoising operation on task performance. The numerical results indicate that, in the cases considered, the application of a denoising network can result in a loss of task-relevant information in the image. The impact of the depth of the denoising networks on task performance is also assessed. The presented results highlight the need for the objective evaluation of IQ for DNN-based denoising technologies and may suggest future avenues for improving their effectiveness in medical imaging applications.

Indexed as

Image Processing, Computer-AssistedNeural Networks, ComputerDiagnostic ImagingTask Performance and Analysis

Identifiers

PMID33929958
PMCPMC8673589

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.