Evidence map›Paper›PMID 33929751›Full record

ArticleImmunology and cell biology2021

Induction of stable human FOXP3

Laura Cook, Kyle T Reid, Elmeri Häkkinen, Brett de Bie, Shigeru Tanaka, Danielle J Smyth, Madeleine Pj White, May Q Wong, Qing Huang, Jana K Gillies and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Immunology and cell biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Laura CookDepartment of Medicine, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0003-3153-2045
Kyle T ReidBC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Elmeri HäkkinenBC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Brett de BieBC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Shigeru TanakaDepartment of Translational Research, Benaroya Research Institute, Virginia Mason, Seattle, WA, USA.ORCID 0000-0002-8466-110X
Danielle J SmythWellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.ORCID 0000-0001-6080-2679
Madeleine Pj WhiteWellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.ORCID 0000-0002-0152-1110
May Q WongDepartment of Medicine, University of British Columbia, Vancouver, BC, Canada.
Qing HuangBC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Jana K GilliesBC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Steven F ZieglerDepartment of Translational Research, Benaroya Research Institute, Virginia Mason, Seattle, WA, USA.
Rick M MaizelsWellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.ORCID 0000-0003-3216-1944
Megan K LevingsBC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-0305-5790
University of British Columbia · CAWellcome Centre for Molecular Parasitology · GBVirginia Mason Medical Center · US

Funding

BC Children's HospitalKenneth Rainin Foundation 2015-964Kenneth Rainin Foundation 2016-3067Medical Research Council MC_PC_18048Wellcome TrustWellcome Trust 104111Wellcome Trust 106122
6 · The paper itself

Abstract

Immune homeostasis in the intestine is tightly controlled by FOXP3

Indexed as

ParasitesAnimalsForkhead Transcription FactorsHumansTh17 CellsT-Lymphocytes, RegulatoryTransforming Growth Factor betaForkhead Transcription FactorsFOXP3 protein, humanTransforming Growth Factor betahost parasite interactionsinflammatory diseaseregulatory T cellstransforming growth factor beta

Identifiers

PMID33929751
PMCPMC8453874
OpenAlexW3157240979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.