Evidence map›Paper›PMID 33929713›Full record

ReviewTissue engineering and regenerative medicine2021

Comparison of Autogenous Tooth Materials and Other Bone Grafts.

Shuxin Zhang, Xuehan Li, Yanxin Qi, Xiaoqian Ma, Shuzhan Qiao, HongXin Cai, Bing Cheng Zhao, Heng Bo Jiang, Eui-Seok Lee

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Tissue engineering and regenerative medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06879171 (Radiographic and Histomorphometric Assessment for Alveolar Ridge Preservation Using Autogenous Tooth Graft From Extracted Tooth Combined With Simvastatin 1), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06879171 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Radiographic and Histomorphometric Assessment for Alveolar Ridge Preservation Using Autogenous Tooth Graft From Extracted Tooth Combined With Simvastatin 1:1 Versus Autogenous Tooth Graft: A Randomized Clinical Trial (RCT)

TypeinterventionalSponsorCairo UniversityRan2025 to 2026Enrolled26ConditionsAlveolar Ridge Preservation, Horizontal Alveolar Bone Loss, Vertical Alveolar Bone Loss, Delayed ImplantArmsAlveolar ridge preservation
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 109 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Shuxin Zhang *Stomatological Materials Laboratory, School of Stomatology, Shandong First Medical University, Tai'an, 271016, Shandong, China.
Xuehan Li *Stomatological Materials Laboratory, School of Stomatology, Shandong First Medical University, Tai'an, 271016, Shandong, China.
Yanxin Qi *Stomatological Materials Laboratory, School of Stomatology, Shandong First Medical University, Tai'an, 271016, Shandong, China.
Xiaoqian MaStomatological Materials Laboratory, School of Stomatology, Shandong First Medical University, Tai'an, 271016, Shandong, China.
Shuzhan QiaoStomatological Materials Laboratory, School of Stomatology, Shandong First Medical University, Tai'an, 271016, Shandong, China.
HongXin CaiStomatological Materials Laboratory, School of Stomatology, Shandong First Medical University, Tai'an, 271016, Shandong, China.
Bing Cheng ZhaoStomatological Materials Laboratory, School of Stomatology, Shandong First Medical University, Tai'an, 271016, Shandong, China.
Heng Bo JiangStomatological Materials Laboratory, School of Stomatology, Shandong First Medical University, Tai'an, 271016, Shandong, China. hengbojiang@hotmail.com.ORCID 0000-0002-2514-2633
Eui-Seok LeeDepartment of Oral and Maxillofacial Surgery, Graduate School of Clinical Dentistry, Korea University, Seoul, 02841, Republic of Korea. ees225@hanmail.net.
Shandong First Medical University · CNKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autogenous odontogenic materials are a new, highly biocompatible option for jaw restoration. The inorganic component of autogenous teeth acts as a scaffold to maintain the volume and enable donor cell attachment and proliferation; the organic component contains various growth factors that promote bone reconstruction and repair. The composition of dentin is similar to that of bone, which can be a rationale for promoting bone reconstruction. Recent advances have been made in the field of autogenous odontogenic materials, and studies have confirmed their safety and feasibility after successful clinical application. Autogenous odontogenic materials have unique characteristics compared with other bone-repair materials, such as the conventional autogenous, allogeneic, xenogeneic, and alloplastic bone substitutes. To encourage further research into odontogenic bone grafts, we compared the composition, osteogenesis, and development of autogenous odontogenic materials with those of other bone grafts. In conclusion, odontogenic bone grafts should be classified as a novel bone substitute.

Indexed as

Bone SubstitutesToothBone and BonesBone TransplantationOsteogenesisBone SubstitutesAutoBTAutograftBone reconstructionImplantTooth material

Identifiers

PMID33929713
PMCPMC8169722
OpenAlexW3158829341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.