Evidence map›Paper›PMID 33929661›Full record

SynthesisAdvances in therapy2021

Efficacy and Safety of Budesonide/Glycopyrronium/Formoterol Fumarate versus Other Triple Combinations in COPD: A Systematic Literature Review and Network Meta-analysis.

Arnaud Bourdin, Nicolas Molinari, Gary T Ferguson, Barinder Singh, Mohd Kashif Siddiqui, Ulf Holmgren, Mario Ouwens, Martin Jenkins, Enrico De Nigris

Open access · hybridAbstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Advances in therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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  16. Beyond Dual Bronchodilation - Triple Therapy, When and Why.International journal of chronic obstructive pulmonary disease
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Arnaud BourdinDepartment of Respiratory Diseases, PhyMedExp, INSERM, CNRS, CHU de Montpellier, Université de Montpellier, Montpellier, France. a-bourdin@chu-montpellier.fr.
Nicolas MolinariIMAG, CNRS, CHU de Montpellier, Université de Montpellier, Montpellier, France.
Gary T FergusonPulmonary Research Institute of Southeast Michigan, Farmington Hills, MI, USA.
Barinder SinghFormerly of Parexel International, Punjab, India.
Mohd Kashif SiddiquiParexel International, Punjab, India.
Ulf HolmgrenAstraZeneca, Gothenburg, Sweden.
Mario OuwensAstraZeneca, Gothenburg, Sweden.
Martin JenkinsAstraZeneca, Cambridge, UK.
Enrico De NigrisAstraZeneca, Cambridge, UK.
AstraZeneca (Sweden) · SEAstraZeneca (United Kingdom) · GBPAREXEL International (India) · INInserm · FRPulmonary Associates · USUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with chronic obstructive pulmonary disease (COPD) who experience further exacerbations or symptoms, despite being prescribed dual long-acting muscarinic antagonist (LAMA)/long-acting β

Indexed as

GlycopyrrolatePulmonary Disease, Chronic ObstructiveAdministration, InhalationAdrenergic beta-2 Receptor AgonistsBayes TheoremBronchodilator AgentsBudesonideDrug CombinationsFormoterol FumarateFumaratesHumansMuscarinic AntagonistsQuality of LifeAdrenergic beta-2 Receptor AgonistsBronchodilator AgentsBudesonideDrug CombinationsFormoterol FumarateFumaratesGlycopyrrolateMuscarinic AntagonistsChronic obstructive pulmonary diseaseExacerbationsInhaled corticosteroidLong-acting muscarinic antagonistLong-acting β2-agonistLung functionNetwork meta-analysisPatient-reported outcomesSafetyTriple therapy

Identifiers

PMID33929661
PMCPMC8189959
OpenAlexW3159046084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.