ArticleBasic research in cardiology2021
Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.
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Article in Basic research in cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 35 citations in OpenAlex.
- Loss of erythrocyte arginase-1 impairs vasorelaxation due to endothelial GSNOR overexpression and denitrosylation of G protein subunits.Redox biology · 2026Article
- The impact of environmental pollution and climate change on hypertension: a position paper by the European Society of Hypertension (ESH) Working Group on Environment in Hypertension.Cardiovascular research · 2026Review
- A comprehensive review/expert statement on environmental risk factors of cardiovascular disease.Cardiovascular research · 2025Review
- CD40-TRAF6 inhibition suppresses cardiovascular inflammation, oxidative stress and functional complications in a mouse model of arterial hypertension.Redox biology · 2025Article
- Interventions by Cardiovascular Drugs Against Aircraft Noise-Induced Cardiovascular Oxidative Stress and Damage.Antioxidants (Basel, Switzerland) · 2025Article
- Transportation noise pollution as a cardiovascular risk factor: from epidemiological evidence to mechanistic insights.EXCLI journal · 2025Review
- Noise causes cardiovascular disease: it's time to act.Journal of exposure science & environmental epidemiology · 2025Review
- Immune and inflammatory mechanisms in hypertension.Nature reviews. Cardiology · 2024Review
- Health position paper and redox perspectives - Disease burden by transportation noise.Redox biology · 2024Review
- Aircraft noise exposure induces pro-inflammatory vascular conditioning and amplifies vascular dysfunction and impairment of cardiac function after myocardial infarction.Cardiovascular research · 2023Article
- Vascular Redox Signaling, Endothelial Nitric Oxide Synthase Uncoupling, and Endothelial Dysfunction in the Setting of Transportation Noise Exposure or Chronic Treatment with Organic Nitrates.Antioxidants & redox signaling · 2023Review
- Noise, Air, and Heavy Metal Pollution as Risk Factors for Endothelial Dysfunction.European cardiology · 2023Review
- Environmental risk factors and cardiovascular diseases: a comprehensive expert review.Cardiovascular research · 2022Article
- Intraocular Pressure-Induced Endothelial Dysfunction of Retinal Blood Vessels Is Persistent, but Does Not Trigger Retinal Ganglion Cell Loss.Antioxidants (Basel, Switzerland) · 2022Article
- Noise exposure and its relationship with postinfarction cardiac remodeling: implications for NLRP3 inflammasome activation.Bioengineered · 2022Article
- Methods to measure blood flow and vascular reactivity in the retina.Frontiers in medicine · 2022Review
- Angiotensin II Induces Oxidative Stress and Endothelial Dysfunction in Mouse Ophthalmic Arteries via Involvement of AT1 Receptors and NOX2.Antioxidants (Basel, Switzerland) · 2021Article
- Article
- Redox Switches in Noise-Induced Cardiovascular and Neuronal Dysregulation.Frontiers in molecular biosciences · 2021Review
- Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development.Frontiers in molecular biosciences · 2021Article
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Authors and funding
18 authors at 1 institution in 1 country.
Katie FrenisDepartment of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany.ORCID http://orcid.org/0000-0003-4103-0882
Johanna HelmstädterDepartment of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany.
Yue RuanDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Eva SchrammInstitute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Sanela KalinovicDepartment of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany.
Swenja Kröller-SchönDepartment of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany.
Maria Teresa Bayo JimenezDepartment of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany.
Omar HahadDepartment of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany.
Matthias OelzeDepartment of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany.
Subao JiangDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Philip WenzelDepartment of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany.
Clemens J SommerInstitute of Neuropathology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Katrin B M FrauenknechtInstitute of Neuropathology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Ari WaismanInstitute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Adrian GerickeDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Andreas DaiberDepartment of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany. daiber@uni-mainz.de.ORCID http://orcid.org/0000-0002-2769-0094
Thomas Münzel *Department of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany. tmuenzel@uni-mainz.de.
Sebastian Steven *Department of Cardiology, Cardiology I-Laboratory of Molecular Cardiology, University Medical Center of the Johannes Gutenberg-University, Building 605, Langenbeckstr. 1, 55131, Mainz, Germany.
Johannes Gutenberg University Mainz · DE
Funding
Boehringer Ingelheim Stiftung collaborative research group 'Novel and neglected cardiovascular risk factors: molecular mechanisms and therapeutic implications'Deutsches Zentrum für Herz-Kreislaufforschung Partner Site Rhine-Main, MainzElse Kröner-Fresenius-Stiftung 2017_A106Stavros Niarchos Foundation career development grant
Abstract
Aircraft noise induces vascular and cerebral inflammation and oxidative stress causing hypertension and cardiovascular/cerebral dysfunction. With the present studies, we sought to determine the role of myeloid cells in the vascular vs. cerebral consequences of exposure to aircraft noise. Toxin-mediated ablation of lysozyme M
Indexed as
AircraftAnimalsArteriesBrainDisease Models, AnimalEncephalitisGene DeletionInflammation MediatorsMaleMiceMice, Inbred C57BLMice, TransgenicMicrogliaMuramidaseMyeloid CellsNoise, TransportationInflammation Mediatorslysozyme M, mouseMuramidaseReactive Oxygen SpeciesAircraft noise exposureCerebral inflammationDiphtheria toxinEndothelial dysfunctionEnvironmental risk factorMyeloid cell ablationOxidative stress
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.