Evidence map›Paper›PMID 33929533›Full record

ArticleSleep2021

Aerobic and resistance exercise improve patient-reported sleep quality and is associated with cardiometabolic biomarkers in Hispanic and non-Hispanic breast cancer survivors who are overweight or obese: results from a secondary analysis.

Christina M Dieli-Conwright, Kerry S Courneya, Wendy Demark-Wahnefried, Nathalie Sami, Mary K Norris, Frank S Fox, Thomas A Buchanan, Darcy Spicer, Leslie Bernstein, Debu Tripathy

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01140282 (Combined Exercise Program for Early Breast Cancer Survivors), which is not on this map. Cited by 17 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 6 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01140282 nacompletednot on this map

Combined Exercise Program for Early Breast Cancer Survivors

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2012 to 2018Enrolled106ConditionsStage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast CancerArmsquestionnaire administration, quality-of-life assessment, management of therapy complications, exercise intervention
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 6 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  7. Trial
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  9. Review
  10. Lifestyle Behaviors and Health-Related Quality of Life in Cancer Survivors: A Latent Class Analysis.Health education & behavior : the official publication of the Society for Public Health Education · 2024
    Article
  11. Role of exercise in reducing the risk of cardiovascular diseases associated with sleep disorders.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
  12. Article
  13. Metabolic underpinnings of cancer-related fatigue.American journal of physiology. Endocrinology and metabolism · 2024
    Review
  14. Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Christina M Dieli-ConwrightDivision of Population Sciences, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-9093-7259
Kerry S CourneyaFaculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.
Wendy Demark-WahnefriedDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0001-5241-932X
Nathalie SamiDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Mary K NorrisDivision of Population Sciences, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Frank S FoxDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Thomas A BuchananDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Darcy SpicerDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Leslie BernsteinDivision of Biomarkers of Early Detection and Prevention, Beckman Research Institute, COH, Duarte, CA, USA.ORCID 0000-0002-7692-6518
Debu TripathyDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
University of Southern California · USHarvard University · USBeckman Research InstituteThe University of Texas MD Anderson Cancer Center · USUniversity of Alabama at Birmingham · USUniversity of Alberta · CA

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI James O Hill · 2000 to 2026
$31.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Metabolic Syndrome and Breast Cancer: Effects of a Combined Exercise InterventionK07CA160718 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DIELI-CONWRIGHT, CHRISTINA · 2011 to 2015
$629k
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NCI NIH HHS K07 CA160718NCI NIH HHS UL1TR001855NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

STUDY

objectivesPoor sleep quality affects nearly one-third of breast cancer survivors and is associated with insulin resistance. The purpose of this secondary analysis was to examine the effects of a 16-week exercise intervention on patient-reported sleep quality among breast cancer survivors and assess whether changes in patient-reported sleep quality were associated with cardiometabolic biomarkers. We explored Hispanic ethnicity as a moderator of the effects of exercise on patient-reported sleep quality.

methodsBreast cancer survivors who were overweight or obese were randomized to exercise (n = 50) or usual care (n = 50). The 16-week intervention included aerobic and resistance exercise. Patient-reported sleep quality (Pittsburgh Sleep Quality Index [PSQI]) and biomarkers of cardiometabolic health were assessed at baseline and post-intervention. Within- and between-group differences were assessed using general linear models repeated-measures analyses of variance and mixed-model repeated-measure analysis, respectively. Associations between changes in PSQI and cardiometabolic biomarkers were computed using Pearson correlations. Linear mixed-models were used to evaluate effect modification by ethnicity.

resultsParticipants were 52 ± 10.4 years old, and over half were of Hispanic ethnicity. As compared to usual care, PSQI global scores improved significantly in the exercise group (mean between-group difference -2.2; 95% CI -3.2 to -0.6). Change in PSQI was inversely associated with changes in all cardiometabolic biomarkers (p < 0.01) among the exercise group. Ethnicity was found to moderate the effects of exercise training on global sleep quality (p < 0.001).

conclusionsAn aerobic and resistance exercise intervention effectively improved patient-reported sleep quality in breast cancer survivors. Hispanic ethnicity as a moderator showed greater improvement in patient-reported sleep indicating Hispanic versus non-Hispanic breast cancer survivors may derive larger sleep benefits. CLINICAL TRAIL INFORMATION: NCT01140282.

Indexed as

Breast NeoplasmsCancer SurvivorsCardiovascular DiseasesResistance TrainingAdultBiomarkersExerciseFemaleHumansMiddle AgedObesityOverweightPatient Reported Outcome MeasuresQuality of LifeSleepBiomarkersbreast cancerexercisesleep quality

Identifiers

PMID33929533
PMCPMC8503828
OpenAlexW3159031474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.