Evidence map›Paper›PMID 33929291›Full record

ReviewGut microbes

Healthy Intestinal Function Relies on Coordinated Enteric Nervous System, Immune System, and Epithelium Responses.

Fatima B Saldana-Morales, Dasom V Kim, Ming-Ting Tsai, Gretchen E Diehl

Abstract readReview
In one paragraph

Review in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Evaluating the Effect ofNutrients · 2024
    Trial
  2. Intestinal muscularis in health and disease.Communications biology · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Vesicle-like nanoparticles extracted fromExtracellular vesicles and circulating nucleic acids · 2026
    Article
  8. Frontiers in immunology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fatima B Saldana-MoralesGraduate School of Biomedical Sciences, Baylor College of Medicine, Houston TX USA.ORCID 0000-0001-5192-5722
Dasom V KimImmunology Program of the Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY USA.
Ming-Ting TsaiGraduate School of Biomedical Sciences, Baylor College of Medicine, Houston TX USA.
Gretchen E DiehlImmunology Program of the Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY USA.ORCID 0000-0002-1841-2842

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Orchestrating intestinal immunity through microbiota-CX3CR1+ cell interactions R01AI125264 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI GRETCHEN E DIEHL · 2017 to 2026
$4.1M
NCI NIH HHS P30 CA008748NIAID NIH HHS R01 AI125264
6 · The paper itself

Abstract

During both health and disease, a coordinated response between the epithelium, immune system, and enteric nervous system is required for proper intestinal function. While each system responds to a number of common stimuli, their coordinated responses support digestion as well as responses and recovery following injury or pathogenic infections. In this review, we discuss how individual responses to common signals work together to support these critical functions.

Indexed as

Gastrointestinal MicrobiomeHost Microbial InteractionsImmunityEnteric Nervous SystemEpitheliumHumansIntestinal MucosaIntestinesEnteric nervous systemsintestinal epitheliumintestinal microbiotamucosal immune responsemucosal immunity

Identifiers

PMID33929291
PMCPMC8096330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.