Evidence map›Paper›PMID 33929084›Full record

Trial reportPharmacology research & perspectives2021

The 5-HT

Erin J Campbell, Yvonne Bonomo, Adam Pastor, Lisa Collins, Amanda Norman, Peter Galettis, Janice Johnstone, Andrew J Lawrence

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Pharmacology research & perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. ACS omega · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. The Effect of Serotonin 5-HTAddiction biology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Beyond the 5-HTThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Review
  14. Subcortical serotonin 5HTNature communications · 2023
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Erin J CampbellFlorey Institute of Neuroscience and Mental Health, Melbourne Brain Centre, The University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0002-4722-6897
Yvonne BonomoDepartment of Addiction Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Parkville, VIC, Australia.
Adam PastorDepartment of Addiction Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Parkville, VIC, Australia.
Lisa CollinsDepartment of Addiction Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Parkville, VIC, Australia.
Amanda NormanDepartment of Addiction Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Parkville, VIC, Australia.
Peter GalettisSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Janice JohnstoneSchool of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Andrew J LawrenceFlorey Institute of Neuroscience and Mental Health, Melbourne Brain Centre, The University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0001-6836-727X
The University of Melbourne · AUUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol use disorder (AUD) and methamphetamine use disorder (MUD) are prevalent and have high adverse impacts on both the individual and society. Current treatment strategies for these disorders are ineffective at a population level. Lorcaserin, a 5-HT

Indexed as

Alcohol DrinkingMethamphetamineReceptor, Serotonin, 5-HT2CAdultAlcoholicsAnti-Obesity AgentsBenzazepinesFemaleHumansMaleMiddle AgedObesityPilot ProjectsSerotonin 5-HT2 Receptor AgonistsSubstance-Related DisordersSubstance Withdrawal SyndromeAnti-Obesity AgentsBenzazepineslorcaserinMethamphetamineReceptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor Agonists5-HT2C agonistalcoholcravinglorcaserinmethamphetamineserotonin

Identifiers

PMID33929084
PMCPMC8085921
OpenAlexW3158573569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.