Evidence map›Paper›PMID 33928544›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Identification of Follicular T-Cell Subsets in Murine and Human Tissues.

Annette Lahmann, Laura Bauer, Andreas Hutloff

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Annette LahmannChronic Immune Reactions, German Rheumatism Research Centre, A Leibniz Institute, Berlin, Germany.
Laura BauerChronic Immune Reactions, German Rheumatism Research Centre, A Leibniz Institute, Berlin, Germany.
Andreas HutloffChronic Immune Reactions, German Rheumatism Research Centre, A Leibniz Institute, Berlin, Germany. andreas.hutloff@uksh.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular helper T (Tfh) cells play a key role in B cell activation and differentiation. Within recent years, distinct subsets of follicular T cells, including regulatory and cytotoxic T cells, have been identified. Apart from classical Tfh cells in secondary lymphoid organs, Tfh-like cells are found in chronically inflamed nonlymphoid tissues. Here, we provide protocols to identify different follicular T cell subsets in murine and human tissues by flow cytometry. This chapter also contains an immunization protocol for the induction of large numbers of Tfh cells in mice.

Indexed as

Flow CytometryAdoptive TransferAnimalsBiomarkersGerminal CenterHumansImmunizationMiceMice, Inbred C57BLMice, TransgenicPhenotypeReceptors, Antigen, T-CellResearch DesignT-Lymphocyte SubsetsWorkflowBiomarkersReceptors, Antigen, T-CellAdjuvantsFlow cytometryFollicular T cellsGerminal centerNKTfh cellsTfc cellsTfh cellsTfh-like cellsTfr cells

Identifiers

PMID33928544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.