ArticleDysphagia2022
The Effect of Combined Guidance of Botulinum Toxin Injection with Ultrasound, Catheter Balloon, and Electromyography on Neurogenic Cricopharyngeal Dysfunction: A Prospective Study.
Article in Dysphagia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Effect of botulinum toxin injection on cricopharyngeal dysphagia: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- Guidelines for the Use of Botulinum Toxin in Otolaryngology From the Korean Society of Laryngology, Phoniatrics and Logopedics Guideline Task Force.Clinical and experimental otorhinolaryngology · 2023Guideline
- Comparative efficacy of different interventions for post-stroke cricopharyngeal achalasia: a systematic review and network meta-analysis.Frontiers in neurologyPooled it
- Endoscopic botulinum toxin injection combined with balloon dilatation for treatment of cricopharyngeal achalasia in patient with brainstem stroke.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Trial
- Consensus expert recommendations for management of dysphagia during hospital admission in Parkinson's disease.Journal of Parkinson's disease · 2026Review
- Article
- Commentary: Research trends and hotspots of post-stroke dysphagia rehabilitation: a bibliometric study and visualization analysis.Frontiers in neuroscience · 2024Article
- Effect of acupuncture on post-stroke dysphagia: a randomized controlled trial.Frontiers in neurology · 2024Article
- Computed tomography in measuring electrode insertion angle and depth for cricopharyngeal muscle electromyography.Quantitative imaging in medicine and surgery · 2023Article
- Characteristics of post-stroke dysphagia: A retrospective study based on FEES.Brain and behavior · 2023Article
- Review
- Botulinum toxin injection combined with traditional swallowing rehabilitation improved cricopharyngeal dysfunction in neuromyelitis optica spectrum disorder: A case report.Frontiers in neurology · 2022Article
- Case report: A case of novel treatment for retrograde cricopharyngeal dysfunction.Frontiers in neurology · 2022Article
- Characteristics of dysphagia among different lesion sites of stroke: A retrospective study.Frontiers in neuroscience · 2022Article
- Emerging Role of Ultrasound in Dysphagia Assessment and Intervention: A Narrative Review.Frontiers in rehabilitation sciences · 2021Review
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCricopharyngeal botulinum toxin (BTX) injection is one of the treatments for neurogenic cricopharyngeal dysfunction (CPD). We conducted this prospective study to investigate the effect and safety of BTX injection for neurogenic CPD with a novel guidance.
methodsTwenty-one patients with neurogenic CPD whose symptoms did not reduce after conventional swallowing therapy were included in this study. The impact of BTX injection on the swallowing function of the patients was evaluated. KEY
resultsAfter the injection, the Functional Oral Intake Scale (FOIS) score increased in 17 of 21 patients (80.9%), which ranged from 1 to 3 (P < 0.001). Moreover, there was a significant reduction in the UES opening impairment (P < 0.01), UES residual pressure (P < 0.05), duration of UES relaxation, penetration-aspiration scale score (P < 0.05), secretion (P < 0.05), vallecular residue (P < 0.01), and left (P < 0.05) and right (P < 0.05) pyriform sinus residue. With at least 6 months of follow-up, we found that FOIS continued to increase in patients who showed improvement after the injection (i.e., FOIS 5-7 points), while it remained unchanged in patients without improvement after the injection. There were no side effects reported in this study. CONCLUSION & INFERENCES: BTX injection into the cricopharyngeal muscle guided by ultrasound, catheter balloon, and electromyography possibly has a long-lasting effect that can effectively and safely improve the swallowing function of patients with neurogenic CPD.
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