Evidence map›Paper›PMID 33928401›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Dosimetry and optimal scan time of [

Leonie Beyer, Astrid Gosewisch, Simon Lindner, Friederike Völter, Lena M Mittlmeier, Reinhold Tiling, Matthias Brendel, Clemens C Cyran, Marcus Unterrainer, Johannes Rübenthaler and 12 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. High-contrast somatostatin receptor imaging of meningiomas with [¹⁸F]SiTATE PET/CT.European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Review
  3. Estimation of split renal function on PET using the SSTR-targeting radioligands [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Head to head comparison of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. [European journal of nuclear medicine and molecular imaging · 2026
    Article
  6. Validation of SUV thresholds in [¹⁸F]SiTATE PET/CT for accurate meningioma segmentation.European journal of nuclear medicine and molecular imaging · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. [European journal of nuclear medicine and molecular imaging · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Low-activity [EJNMMI physics · 2025
    Article
  15. Observational
  16. Article
  17. Review
  18. Research process of PET tracers for neuroendocrine tumors diagnosis.American journal of nuclear medicine and molecular imaging · 2025
    Review
  19. An ACE2 PET imaging agent derived fromEJNMMI radiopharmacy and chemistry · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Leonie BeyerDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Astrid GosewischDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Simon LindnerDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Friederike VölterDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Lena M MittlmeierDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Reinhold TilingDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Matthias BrendelDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Clemens C CyranDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Marcus UnterrainerDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Johannes RübenthalerDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Christoph J AuernhammerENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumours of the GastroEnteroPancreatic System at the University Hospital of Munich (GEPNET-KUM), University Hospital of Munich, Munich, Germany.
Christine SpitzwegENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumours of the GastroEnteroPancreatic System at the University Hospital of Munich (GEPNET-KUM), University Hospital of Munich, Munich, Germany.
Guido BöningDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
F J GildehausDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Klaus JurkschatFakultät für Chemie und Chemische Biologie, Technische Universität Dortmund, Dortmund, Germany.
Carmen WänglerBiomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany.
Björn WänglerMolecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany.
Ralf SchirrmacherDepartment of Oncology, Division of Oncological Imaging, University of Alberta, Edmonton, Alberta, Canada.
Vera WenterDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Andrei TodicaDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Peter BartensteinDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Harun IlhanDepartment of Nuclear Medicine, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany. harun.ilhan@med.uni-muenchen.de.ORCID 0000-0003-0409-1942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRadiolabelled somatostatin analogues targeting somatostatin receptors (SSR) are well established for combined positron emission tomography/computer tomography (PET/CT) imaging of neuroendocrine tumours (NET). [

methodsEight NET patients received a [

resultsAfter 1 h, normal organs showed similar tracer uptake with only negligible changes until 3 h post-injection. In contrast, tracer uptake by tumours increased progressively for almost all types of metastases, thus increasing tumour-to-background ratios over time. Dosimetry resulted in a total effective dose of 0.015 ± 0.004 mSv/MBq. Visual evaluation revealed no clinically relevant discrepancies between later scan times, but image quality was rated highest in 60 and 120 min images.

conclusion[

Indexed as

Neuroendocrine TumorsPositron Emission Tomography Computed TomographyAdultComputersFemaleHumansMalePositron-Emission TomographyRadiometryTissue Distribution[18F]SiTATEDosimetryNETPET/CT

Identifiers

PMID33928401
PMCPMC8440281

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.