Evidence map›Paper›PMID 33928164›Full record

ArticleBioMed research international2021

Inhibitory Effect of Multimodal Nanoassemblies against Glycative and Oxidative Stress in Cancer and Glycation Animal Models.

Hamda Khan, Mohd Waseem, Mohammad Faisal, Abdulrahman A Alatar, Ahmed A Qahtan, Saheem Ahmad

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Hamda KhanLaboratory of Glycation Biology and Metabolic Disorder, Integral Research Centre-1, Department of Biosciences, Integral University, Lucknow 226026, India.
Mohd WaseemDepartment of Zoology, Jagdam College, Jai Prakash University, Chapra, Bihar, India.
Mohammad FaisalDepartment of Botany and Microbiology, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
Abdulrahman A AlatarDepartment of Botany and Microbiology, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
Ahmed A QahtanDepartment of Botany and Microbiology, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
Saheem AhmadDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Hail, Saudi Arabia.ORCID https://orcid.org/0000-0003-1215-0279
King Saud University · SAIntegral University · INJai Prakash University · INUniversity of Ha'il · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, there has been a progress in the study of glycation reaction which is one the possible reason for multiple metabolic disorders. Glycation is a nonenzymatic reaction between nucleic acids, lipids, and proteins resulting into the formation of early glycation products that may further lead to the accumulation of advanced glycation end products (AGEs). The precipitation of AGEs in various cells, tissues, and organs is one of the factors for the initiation and progression of various metabolic derangements including the cancer. The AGE interaction with its receptor "RAGE" activates the inflammatory pathway; yet, the downregulation of RAGE and its role in these pathways are not clear. We explore the effect of anticancer novel nanoassemblies on AGEs to determine its role in the regulation of the expression of RAGE, NFƙB, TNF-

Indexed as

Oxidative StressA549 CellsAnimalsBenzothiazolesBlood GlucoseCarbocyaninesCell ProliferationDisease Models, AnimalGlycosylationHumansInterferon-gammaLung NeoplasmsMCF-7 CellsMiceModels, BiologicalNanoparticlesBenzothiazolesBlood GlucoseCarbocyaninescyanine dye 7Interferon-gammaNF-kappa BReactive Oxygen SpeciesReceptor for Advanced Glycation End ProductsSerum Albumin, HumanTrifluridineTumor Necrosis Factor-alpha

Identifiers

PMID33928164
PMCPMC8053050
OpenAlexW3155800132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.