Evidence map›Paper›PMID 33927377›Full record

ArticleGenetics in medicine : official journal of the American College of Medical Genetics2021

Approaches to assessing the provider experience with clinical pharmacogenomic information: a scoping review.

Nicholas J Keeling, Tyler J Dunn, John P Bentley, Sujith Ramachandran, James M Hoffman, Meagen Rosenthal

Abstract readScoping Review
In one paragraph

Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Evaluation of the Integration of Genetics and Genomics Into Nursing Practice.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2026
    Article
  4. Observational
  5. Article
  6. Article
  7. Overcoming Barriers to Discovery and Implementation of Equitable Pharmacogenomic Testing in Oncology.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicholas J KeelingDepartment of Pharmacy Administration, University of Mississippi School of Pharmacy, University, MS, USA.
Tyler J DunnDepartment of Pharmacy Administration, University of Mississippi School of Pharmacy, University, MS, USA. tdunn@go.olemiss.edu.
John P BentleyDepartment of Pharmacy Administration, University of Mississippi School of Pharmacy, University, MS, USA.
Sujith RamachandranDepartment of Pharmacy Administration, University of Mississippi School of Pharmacy, University, MS, USA.
James M HoffmanDepartment of Pharmaceutical Sciences and Office of Quality and Patient Care, St. Jude Children's Research Hospital, Memphis, TN, USA.
Meagen RosenthalDepartment of Pharmacy Administration, University of Mississippi School of Pharmacy, University, MS, USA.

Funding

Clinical Pharmacogenetics Implementation Consortium (CPIC)U24HG010135 · NHGRI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CAUDLE, KELLY E., KLEIN, TERI ELLEN · 2018 to 2022
$5.4M
Clinical Pharmacogenetics Implementation Consortium (CPIC)R24GM115264 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KLEIN, TERI ELLEN, RELLING, MARY V · 2015 to 2017
$3.6M
NHGRI NIH HHS U24 HG010135NIGMS NIH HHS R24 GM115264
6 · The paper itself

Abstract

purposeBarriers to the implementation of pharmacogenomics in clinical practice have been thoroughly discussed over the past decade.

methodsThe objective of this scoping review was to characterize the peer-reviewed literature surrounding the experiences and actions of prescribers, pharmacists, or genetic counselors when using pharmacogenomic information in real-world or hypothetical research settings.

resultsA total of 33 studies were included in the scoping review. The majority of studies were conducted in the United States (70%), used quantitative or mixed methods (79%) with physician or pharmacist respondents (100%). The qualitative content analysis revealed five major methodological approaches: hypothetical clinical case scenarios, real-world studies evaluating prescriber response to recommendations or alerts, cross-sectional quantitative surveys, cross-sectional qualitative surveys/interviews, and a quasi-experimental real-world study.

conclusionThe findings of this scoping review can guide further research on the factors needed to successfully integrate pharmacogenomics into clinical care.

Indexed as

PharmacogeneticsPhysiciansCross-Sectional StudiesHumansPharmacistsUnited States

Identifiers

PMID33927377
PMCPMC8817227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.