Evidence map›Paper›PMID 33927356›Full record

ReviewEye (London, England)2021

A review of acquired blepharoptosis: prevalence, diagnosis, and current treatment options.

Jason Bacharach, Wendy W Lee, Andrew R Harrison, Thomas F Freddo

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Eye (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07003308 (Comparative Study of the Efficacy of Anterior Versus Posterior White Line Advancement Technique in the Correction of Primary Aponeurotic Ptosis), which is not on this map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07003308 narecruitingnot on this mapstarted 2025, after this paper: background citation

Comparative Study of the Efficacy of Anterior Versus Posterior White Line Advancement Technique in the Correction of Primary Aponeurotic Ptosis

TypeinterventionalSponsorInstituto de Investigación Sanitaria de la Fundación Jiménez DíazRan2025 to 2027Enrolled54ConditionsPtosis, EyelidArmsAnterior White Line Advancement Surgery, Posterior White Line Advancement Surgery
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Review
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  13. Prospective study of blepharoptosis after plaque radiotherapy.Canadian journal of ophthalmology. Journal canadien d'ophtalmologie · 2026
    Article
  14. Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Jason BacharachNorth Bay Eye Associates, Petaluma, CA, USA. jbacharach@northbayeye.com.ORCID http://orcid.org/0000-0002-7084-4327
Wendy W LeeBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Andrew R HarrisonDepartment of Ophthalmology and Visual Neurosciences, Department of Otolaryngology, University of Minnesota, Minneapolis, MN, USA.
Thomas F FreddoMassachusetts College of Pharmacy and Health Sciences, Worcester, MA, USA.
Bay Medical Center · USMassachusetts College of Pharmacy and Health Sciences · USUniversity of Miami · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blepharoptosis (ptosis) is among the most common disorders of the upper eyelid encountered in both optometric and ophthalmic practice. The unilateral or bilateral drooping of the upper eyelid that characterises ptosis can affect appearance and impair visual function, both of which can negatively impact quality of life. While there are several known forms of congenital ptosis, acquired ptosis (appearing later in life, due to a variety of causes) is the predominant form of the condition. This review summarises the prevalence, causes, identification, differential diagnosis, and treatment of acquired ptosis. Particular attention is paid to the differential diagnosis of acquired ptosis and emerging treatment options, including surgical and pharmacologic approaches.

Indexed as

BlepharoplastyBlepharoptosisEyelidsHumansPrevalenceQuality of Life

Identifiers

PMID33927356
PMCPMC8376882
OpenAlexW3158388127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.