ArticleScientific reports2021
Tracing the origin of the crayfish plague pathogen, Aphanomyces astaci, to the Southeastern United States.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 50 citations in OpenAlex.
- Diversity and Prevalence of Fungi Associated with Freshwater Crayfish in Three Regions of Lithuania: A First Assessment.Microorganisms · 2026Article
- Comparative Genomics Provide Insight Into the Evolution of European Aphanomyces euteiches Strains.Genome biology and evolution · 2026Article
- Prevalence and diversity ofParasitology · 2025Article
- Morphological description and molecular characterization of Heterospinus mccordi n. gen. n. sp. (Acanthocephala: Polymorphidae) from cystacanths infecting a non-native crayfish host, Procambarus clarkii (Decapoda: Cambaridae), in South Carolina, USA.Systematic parasitology · 2024Article
- Crayfish population size under different routes of pathogen transmission.Ecology and evolution · 2023Article
- Host-pathogen coevolution drives innate immune response to Aphanomyces astaci infection in freshwater crayfish: transcriptomic evidence.BMC genomics · 2022Article
- Resistance to Crayfish Plague: Assessing the Response of Native Iberian Populations of the White-Clawed Freshwater Crayfish.Journal of fungi (Basel, Switzerland) · 2022Article
- Article
- Virome Analysis of Signal Crayfish (Viruses · 2021Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The oomycete Aphanomyces astaci is an emerging infectious pathogen affecting freshwater crayfish worldwide and is responsible for one of the most severe wildlife pandemics ever reported. The pathogen has caused mass mortalities of freshwater crayfish species in Europe and Asia, and threatens other susceptible species in Madagascar, Oceania and South America. The pathogen naturally coexists with some North American crayfish species that are its chronic carriers. Presumptions that A. astaci originated in North America are based on disease outbreaks that followed translocations of North American crayfish and on the identification of the pathogen mainly in Europe. We studied A. astaci in the southeastern US, a center of freshwater crayfish diversity. In order to decipher the origin of the pathogen, we investigated (1) the distribution and haplotype diversity of A. astaci, and (2) whether there are crayfish species-specificities and/or geographical restrictions for A. astaci haplotypes. A total of 132 individuals, corresponding to 19 crayfish species and one shrimp species from 23 locations, tested positive for A. astaci. Mitochondrial rnnS and rnnL sequences indicated that A. astaci from the southeastern US exhibited the highest genetic diversity so far described for the pathogen (eight haplotypes, six of which we newly describe). Our findings that A. astaci is widely distributed and genetically diverse in the region supports the hypothesis that the pathogen originated in the southeastern US. In contrast to previous assumptions, however, the pathogen exhibited no clear species-specificity or geographical patterns.
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