Evidence map›Paper›PMID 33927278›Full record

Trial reportScientific reports2021

A randomized sham-controlled trial on the effect of continuous positive airway pressure treatment on gait control in severe obstructive sleep apnea patients.

Sébastien Baillieul, Bernard Wuyam, Dominic Pérennou, Renaud Tamisier, Sébastien Bailly, Meriem Benmerad, Céline Piscicelli, Thibault Le Roux-Mallouf, Samuel Vergès, Jean-Louis Pépin

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02345694 (Non-automatic Control of Gait and Posture in Obstructive Sleep Apnea Syndrome), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02345694 nacompletednot on this map

Non-automatic Control of Gait and Posture in Obstructive Sleep Apnea Syndrome : a Randomised Controlled Trial of Continuous Positive Airway Pressure Effectiveness (CIH - Gait)

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2015 to 2018Enrolled24ConditionsObstructive Sleep Apnea SyndromeArmsEffective CPAP, Sub-therapeutic CPAP
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sébastien BaillieulHP2 Laboratory, U1300, INSERM, Grenoble Alpes University, Grenoble, France.
Bernard WuyamHP2 Laboratory, U1300, INSERM, Grenoble Alpes University, Grenoble, France.
Dominic PérennouLPNC Laboratory (UMPR CNRS 5105), Grenoble Alpes University, Grenoble, France.
Renaud TamisierHP2 Laboratory, U1300, INSERM, Grenoble Alpes University, Grenoble, France.
Sébastien BaillyHP2 Laboratory, U1300, INSERM, Grenoble Alpes University, Grenoble, France.
Meriem BenmeradHP2 Laboratory, U1300, INSERM, Grenoble Alpes University, Grenoble, France.
Céline PiscicelliLPNC Laboratory (UMPR CNRS 5105), Grenoble Alpes University, Grenoble, France.
Thibault Le Roux-MalloufHP2 Laboratory, U1300, INSERM, Grenoble Alpes University, Grenoble, France.
Samuel Vergès *HP2 Laboratory, U1300, INSERM, Grenoble Alpes University, Grenoble, France.
Jean-Louis Pépin *HP2 Laboratory, U1300, INSERM, Grenoble Alpes University, Grenoble, France. jpepin@chu-grenoble.fr.
Université Grenoble Alpes · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine the effect of continuous positive airway pressure (CPAP), the gold standard treatment for obstructive sleep apnea syndrome (OSAS), on gait control in severe OSAS patients. We conducted a randomized, double-blind, parallel-group, sham-controlled monocentric study in Grenoble Alpes University Hospital, France. Gait parameters were recorded under single and dual-task conditions using a visuo-verbal cognitive task (Stroop test), before and after the 8-week intervention period. Stride-time variability, a marker of gait control, was the primary study endpoint. Changes in the determinants of gait control were the main secondary outcomes. ClinicalTrials.gov Identifier: (NCT02345694). 24 patients [median (Q1; Q3)]: age: 59.5 (46.3; 66.8) years, 87.5% male, body mass index: 28.2 (24.7; 29.8) kg. m

Indexed as

Continuous Positive Airway PressureGaitAdultAgedCerebrovascular CirculationCognitionDouble-Blind MethodFemaleHumansMaleMiddle AgedPostural BalanceSleep Apnea, Obstructive

Identifiers

PMID33927278
PMCPMC8085224
OpenAlexW3157232390

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.