Evidence map›Paper›PMID 33927247›Full record

ArticleScientific reports2021

Understanding the role of aerobic fitness, spatial learning, and hippocampal subfields in adolescent males.

Sandhya Prathap, Bonnie J Nagel, Megan M Herting

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Hippocampal Subfield Volumes in Amateur Marathon Runners.Medicine and science in sports and exercise · 2023
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sandhya PrathapDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, 90023, USA.
Bonnie J NagelDepartments of Psychiatry and Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, 97239, USA.
Megan M HertingDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, 90023, USA. Herting@usc.edu.

Funding

Timing Effects of Heavy Alcohol Initiation on Adolescent NeurodevelopmentR01AA017664 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI NAGEL, BONNIE J · 2009 to 2020
$3.7M
The Influence of Fetal Testosterone on Emotional Processing, Amydala Neurocircuitry, and Risk for Affective Disorders in ChildhoodK01MH108761 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HERTING, MEGAN MARIE · 2016 to 2019
$726k
Adolescent Working Memory and White Matter DevelopmentK08NS052147 · NINDS · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI NAGEL, BONNIE J · 2005 to 2009
$666k
Exercise and Hippocampal Structure and Function in AdolescentsF31AA019866 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI HERTING, MEGAN MARIE · 2010 to 2011
$83k
NIAAA NIH HHS R01 AA017664U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) K01MH108761U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) K08NS052147U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) F31AA019866
6 · The paper itself

Abstract

Physical exercise during adolescence, a critical developmental window, can facilitate neurogenesis in the dentate gyrus and astrogliogenesis in Cornu Ammonis (CA) hippocampal subfields of rats, and which have been associated with improved hippocampal dependent memory performance. Recent translational studies in humans also suggest that aerobic fitness is associated with hippocampal volume and better spatial memory during adolescence. However, associations between fitness, hippocampal subfield morphology, and learning capabilities in human adolescents remain largely unknown. Employing a translational study design in 34 adolescent males, we explored the relationship between aerobic fitness, hippocampal subfield volumes, and both spatial and verbal memory. Aerobic fitness, assessed by peak oxygen utilization on a high-intensity exercise test (VO

Indexed as

Cardiorespiratory FitnessAdolescentCA1 Region, HippocampalExercise TestHumansMagnetic Resonance ImagingMaleOxygen ConsumptionSpatial LearningVerbal Learning

Identifiers

PMID33927247
PMCPMC8084987

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.