Evidence map›Paper›PMID 33927212›Full record

Trial reportScientific reports2021

Using supraglottic airways by paramedics for airway management in analogue microgravity increases speed and success of ventilation.

Jochen Hinkelbein, Anton Ahlbäck, Christine Antwerber, Lisa Dauth, James DuCanto, Elisabeth Fleischhammer, Carlos Glatz, Steffen Kerkhoff, Alexander Mathes, Thais Russomano and 4 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 5 countries.

Jochen HinkelbeinDepartment of Anaesthesiology and Intensive Care Medicine, Medical Faculty, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany. jochen.hinkelbein@uk-koeln.de.
Anton AhlbäckSpace Medicine Group, European Society of Aerospace Medicine (ESAM), Cologne, Germany.
Christine AntwerberDepartment of Anaesthesiology and Intensive Care Medicine, Medical Faculty, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Lisa DauthDepartment for Anaesthesiology and Intensive Care Medicine, St. Elisabeth Hospital, Cologne, Germany.
James DuCantoDepartment of Anaesthesiology, Medical College of Wisconsin, Aurora St. Luke's Medical Center, Milwaukee, USA.
Elisabeth FleischhammerDepartment of Anaesthesiology and Intensive Care Medicine, Medical Faculty, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Carlos GlatzDepartment of Medicine, Goethe University Frankfurt am Main, Frankfurt, Germany.
Steffen KerkhoffDepartment of Anaesthesiology and Intensive Care Medicine, Medical Faculty, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Alexander MathesDepartment of Anaesthesiology and Intensive Care Medicine, Medical Faculty, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Thais RussomanoCentre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, Kings College London, London, UK.
Jan SchmitzDepartment of Anaesthesiology and Intensive Care Medicine, Medical Faculty, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Clement StarckSpace Medicine Group, European Society of Aerospace Medicine (ESAM), Cologne, Germany.
Seamus ThierrySpace Medicine Group, European Society of Aerospace Medicine (ESAM), Cologne, Germany.
Tobias WarneckeDepartment of Anaesthesiology, Critical Care, Emergency Medicine and Pain Therapy, Hospital of Oldenburg, Medical Campus University of Oldenburg, Oldenburg, Germany.
European Astronaut Centre · DEUniversity Hospital Cologne · DEAurora St. Luke's Medical Center · USCarl von Ossietzky Universität Oldenburg · DEGoethe University Frankfurt · DEKing's College London · GBSt. Elisabeth-Hospital Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the next few years, the number of long-term space missions will significantly increase. Providing safe concepts for emergencies including airway management will be a highly challenging task. The aim of the present trial is to compare different airway management devices in simulated microgravity using a free-floating underwater scenario. Five different devices for airway management [laryngeal mask (LM), laryngeal tube (LT), I-GEL, direct laryngoscopy (DL), and video laryngoscopy (VL)] were compared by n = 20 paramedics holding a diving certificate in a randomized cross-over setting both under free-floating conditions in a submerged setting (pool, microgravity) and on ground (normogravity). The primary endpoint was the successful placement of the airway device. The secondary endpoints were the number of attempts and the time to ventilation. A total of 20 paramedics (3 female, 17 male) participated in this study. Success rate was highest for LM and LT and was 100% both during simulated microgravity and normogravity followed by the I-GEL (90% during microgravity and 95% during normogravity). However, the success rate was less for both DL (60% vs. 95%) and VL (20% vs. 60%). Fastest ventilation was performed with the LT both in normogravity (13.7 ± 5.3 s; n = 20) and microgravity (19.5 ± 6.1 s; n = 20). For the comparison of normogravity and microgravity, time to ventilation was shorter for all devices on the ground (normogravity) as compared underwater (microgravity). In the present study, airway management with supraglottic airways and laryngoscopy was shown to be feasible. Concerning the success rate and time to ventilation, the optimum were supraglottic airways (LT, LM, I-GEL) as their placement was faster and associated with a higher success rate. For future space missions, the use of supraglottic airways for airway management seems to be more promising as compared to tracheal intubation by DL or VL.

Indexed as

Airway ManagementAllied Health PersonnelRespirationSpace FlightWeightlessnessCross-Over StudiesFemaleHumansIntubation, IntratrachealLaryngeal MasksLaryngoscopesLaryngoscopyMaleManikins

Identifiers

PMID33927212
PMCPMC8085007
OpenAlexW3157739777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.