Evidence map›Paper›PMID 33926963›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Structure and activity of SLAC1 channels for stomatal signaling in leaves.

Ya-Nan Deng, Hamdy Kashtoh, Quan Wang, Guang-Xiao Zhen, Qi-Yu Li, Ling-Hui Tang, Hai-Long Gao, Chun-Rui Zhang, Li Qin, Min Su and 7 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. OPEN STOMATA 1 activates SLAC1 anion channel primarily through CPK15 in ABA-induced stomatal closure inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Rice Responses to Abiotic Stress: Key Proteins and Molecular Mechanisms.International journal of molecular sciences · 2025
    Review
  14. Hyperosmolarity-induced suppression of group B1 Raf-like protein kinases modulates drought-growth trade-off inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Mechanistic insights into phosphoactivation of SLAC1 in guard cell signaling.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ya-Nan DengState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.ORCID 0000-0002-1383-4368
Hamdy KashtohState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.ORCID 0000-0002-6377-1115
Quan WangNational Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101 Beijing, China.
Guang-Xiao ZhenState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.ORCID 0000-0001-8723-1810
Qi-Yu LiState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.
Ling-Hui TangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.
Hai-Long GaoNational Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101 Beijing, China.ORCID 0000-0002-7627-9285
Chun-Rui ZhangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.
Li QinState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.
Min SuState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.
Fei LiDepartment of Biology, New York University, New York, NY 10003.
Xia-He HuangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.
Ying-Chun WangState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.
Qi XieState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China.ORCID 0000-0002-8262-9093
Oliver B ClarkeDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032; oc2188@cumc.columbia.edu wah2@cumc.columbia.edu yuhang.chen@genetics.ac.cn.ORCID 0000-0003-1876-196X
Wayne A HendricksonDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032; oc2188@cumc.columbia.edu wah2@cumc.columbia.edu yuhang.chen@genetics.ac.cn.
Yu-Hang ChenState Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101 Beijing, China; oc2188@cumc.columbia.edu wah2@cumc.columbia.edu yuhang.chen@genetics.ac.cn.

Funding

Training (303-338)P41GM116799 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI HENDRICKSON, WAYNE A. · 2016 to 2020
$7.1M
Molecular Basis of Centromere Specification and InheritanceR35GM134920 · NIGMS · NEW YORK UNIVERSITY · PI LI, FEI · 2020 to 2025
$4.2M
Proposal for an Administrative Supplement for Equipment Purchases for NIGMS Awardees NOT-GM-18-022R01GM107462 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HENDRICKSON, WAYNE A. · 2014 to 2021
$3.6M
NIGMS NIH HHS P41 GM116799NIGMS NIH HHS R01 GM107462NIGMS NIH HHS R35 GM134920
6 · The paper itself

Abstract

Stomata in leaves regulate gas exchange between the plant and its atmosphere. Various environmental stimuli elicit abscisic acid (ABA); ABA leads to phosphoactivation of slow anion channel 1 (SLAC1); SLAC1 activity reduces turgor pressure in aperture-defining guard cells; and stomatal closure ensues. We used electrophysiology for functional characterizations of

Indexed as

Abscisic AcidAnionsArabidopsisArabidopsis ProteinsBrachypodiumCarbon DioxideCryoelectron MicroscopyIon TransportMembrane ProteinsPhosphorylationPlant LeavesPlant StomataProtein ConformationSignal TransductionAbscisic AcidAnionsArabidopsis ProteinsCarbon DioxideMembrane ProteinsSLAC1 protein, Arabidopsisabscisic acid signalingchannel activationcryo-EMelectrophysiologyphosphorylation

Identifiers

PMID33926963
PMCPMC8106318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.