Evidence map›Paper›PMID 33926682›Full record

ReviewRadiologic clinics of North America2021

Clinical Applications of Magnetic Resonance Spectroscopy in Brain Tumors: From Diagnosis to Treatment.

Brent D Weinberg, Manohar Kuruva, Hyunsuk Shim, Mark E Mullins

Open access · greenAbstract readReview
In one paragraph

Review in Radiologic clinics of North America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. The etiological spectrum of multiple ring-enhancing lesions of the brain: a systematic review of published cases and case series.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
  3. Review
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  11. A Fast and Precise Method to Search for Desirable Rectangular Tumor Regions in Brain MR Images.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brent D WeinbergRadiology and Imaging Sciences, Emory University, 1364 Clifton Road Northeast BG20, Atlanta, GA 30322, USA. Electronic address: brent.d.weinberg@emory.edu.
Manohar KuruvaRadiology and Imaging Sciences, Emory University, 1364 Clifton Road Northeast BG20, Atlanta, GA 30322, USA.
Hyunsuk ShimRadiation Oncology, Emory University, 1365 Clifton Road Northeast, Atlanta, GA 30322, USA.
Mark E MullinsRadiology and Imaging Sciences, Emory University, 1364 Clifton Road Northeast BG20, Atlanta, GA 30322, USA.
Emory Healthcare · US

Funding

Improved Whole-Brain Spectroscopic MRI for Radiation Treatment PlanningU01EB028145 · NIBIB · EMORY UNIVERSITY · PI COOPER, LEE, HAN, HUI · 2018 to 2020
$2.4M
NIBIB NIH HHS U01 EB028145
6 · The paper itself

Abstract

Magnetic resonance spectroscopy (MRS) is a valuable tool for imaging brain tumors, primarily as an adjunct to conventional imaging and clinical presentation. MRS is useful in initial diagnosis of brain tumors, helping differentiate tumors from possible mimics such as metastatic disease, lymphoma, demyelination, and infection, as well as in the subsequent follow-up of patients after resection and chemoradiation. Unfortunately, the spectroscopic appearance of many pathologies can overlap, and ultimately follow-up or biopsy may be required to make a definitive diagnosis. Future developments may continue to increase the value of MRS for initial diagnosis, treatment planning, and early detection of recurrence.

Indexed as

BrainBrain NeoplasmsDiagnosis, DifferentialHumansMagnetic Resonance SpectroscopyBrain tumorGlioblastomaMagnetic resonance spectroscopyPseudoprogressionRadiation necrosisTumor progression

Identifiers

PMID33926682
PMCPMC8272438
OpenAlexW3138098961

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.