Evidence map›Paper›PMID 33926591›Full record

Trial reportInternational psychogeriatrics2021

PROTECT: a novel psychotherapy for late-life depression in elder abuse victims.

Jo Anne Sirey, Nili Solomonov, Arielle Guillod, Paula Zanotti, Jihui Lee, Mohamed Soliman, George S Alexopoulos

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International psychogeriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Improving Adherence to Psychotherapy and Clinical Outcome in Patients With Late-Life Depression Through Gamified mHealth Technology.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026
    Article
  5. Psychotherapy for older adults with depression: a narrative review.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  6. PTSD in Elder Abuse Survivors: Trauma Symptom Presentation and Treatment Outcomes With the PROTECT Intervention.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025
    Article
  7. Article
  8. Reducing Depression and Suicidal Ideation Among Elder Abuse Victims Using PROTECT.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025
    Article
  9. Improved outcomes for depressed elder abuse victims with video-delivered psychotherapy during COVID-19.Psychotherapy research : journal of the Society for Psychotherapy Research · 2025
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jo Anne SireyDepartment of Psychiatry, Weill Cornell Medicine, White Plains, NY10605, USA.
Nili SolomonovDepartment of Psychiatry, Weill Cornell Medicine, White Plains, NY10605, USA.
Arielle GuillodDepartment of Psychiatry, Weill Cornell Medicine, White Plains, NY10605, USA.
Paula ZanottiDepartment of Psychiatry, Weill Cornell Medicine, White Plains, NY10605, USA.
Jihui LeeDepartment of Population Health Sciences, Weill Cornell Medicine, White Plains, New York, NY10605, USA.
Mohamed SolimanDepartment of Psychiatry, Weill Cornell Medicine, White Plains, NY10605, USA.
George S AlexopoulosDepartment of Psychiatry, Weill Cornell Medicine, White Plains, NY10605, USA.
Weill Cornell Medicine · USCornell University · US

Funding

Relief: A Behavioral Intervention for Depression and Chronic Pain for Primary Care PracticesP50MH113838 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI SIREY, JO ANNE · 2017 to 2020
$5.7M
RESEARCH TRAINING IN GERIATRIC MOOD DISORDERST32MH019132 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUNNING, FAITH M · 1990 to 2025
$3.4M
Positive valence systems engagement during social reward exposure psychotherapy for mid- and late-life depressionK23MH123864 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI SOLOMONOV, NILI · 2020 to 2024
$954k
NIMH NIH HHS K23 MH123864NIMH NIH HHS P50 MH113838NIMH NIH HHS T32 MH019132
6 · The paper itself

Abstract

Elder abuse is prevalent, and victims have high rates of depression and low quality of life. We established an academic-community partnership to test the feasibility, acceptability, and impact of a brief psychotherapy for depression (PROTECT) among elder abuse victims with capacity to make decisions. Elder abuse service providers referred depressed (Patient Health Questionnaire-9 [PHQ-9] ≥ 10) older victims (age ≥ 55 years) for potential pilot study participation. Forty eligible victims who consented were randomized to PROTECT psychotherapy (N = 25) or a Usual Care (N = 15) condition involving a community psychotherapy referral. Follow-up research assessments were conducted at 6 weeks (mid-treatment) and 9 weeks (end of treatment) after study initial assessment. We used mixed-effects regression models to examine treatment effects on depression severity and quality of life over time. Most victims (75%) reported two or more types of abuse. The a priori acceptability benchmark was met at the end of PROTECT therapy. All PROTECT participants initiated therapy; this engagement rate is greater than the a priori 75% standard set for feasibility. We found a significant reduction in depression severity (Montgomery-Åsberg Depression Rating Scale [MADRS]), with PROTECT leading to greater benefits compared to Usual Care. Both study groups had a similar improvement in quality of life. The pilot project results found that PROTECT psychotherapy is feasible, acceptable, and effective in reducing depression. With the support of our partnership, we found that PROTECT could be delivered alongside elder abuse services with victims willing to initiate therapy that leads to meaningful treatment effects.

Indexed as

AgedAged, 80 and overDepressionElder AbuseFemaleHealth Services for the AgedHumansMalePilot ProjectsPsychotherapyQuality of Lifeagingbehavioral therapycommunity interventionelder abuselate-life depressionpsychotherapy outcome

Identifiers

PMID33926591
PMCPMC8169597
OpenAlexW3157184860

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.