Evidence map›Paper›PMID 33926389›Full record

ArticleBMC infectious diseases2021

The Selvester QRS score as an estimative of myocardial injury in acute chagasic patients from the Brazilian Amazon.

Katia do Nascimento Couceiro, Jessica Vanina Ortiz, Michael do Nascimento Correia, Mônica Regina Hosannah da Silva E Silva, Alba Regina Brandão, Paula Rita Leite da Silva, Susan Smith Doria, Reinaldo Bulgarelli Bestetti, Débora Raysa Teixeira de Sousa, Rubens Celso Andrade da Silva Junior and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Overview of Chagas disease in Amazonas: an integrated approach.Revista da Sociedade Brasileira de Medicina Tropical · 2026
    Review
  3. Acute micro-outbreak of Chagas disease in the southeastern Amazon: a report of five cases.Revista da Sociedade Brasileira de Medicina Tropical · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Katia do Nascimento Couceiro *Programa de Pós Graduação em Medicina Tropical, Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil. kcouceiro@cardiol.br.ORCID http://orcid.org/0000-0001-6446-8858
Jessica Vanina Ortiz *Departamento de Ciências Fisiológicas, Universidade Federal do Amazonas, Manaus, Brazil.
Michael do Nascimento Correia *Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.
Mônica Regina Hosannah da Silva E Silva *Programa de Pós Graduação em Medicina Tropical, Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.
Alba Regina BrandãoEscola de Medicina, Universidade Federal do Amazonas, Manaus, Brazil.
Paula Rita Leite da SilvaPrograma de Pós Graduação em Medicina Tropical, Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.
Susan Smith DoriaPrograma de Pós Graduação em Medicina Tropical, Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.
Reinaldo Bulgarelli BestettiEscola de Medicina, Universidade de Ribeirão Preto, São Paulo, Brazil.
Débora Raysa Teixeira de SousaPrograma de Pós Graduação em Medicina Tropical, Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.
Rubens Celso Andrade da Silva JuniorPrograma de Pós Graduação em Medicina Tropical, Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.
Maria das Graças Vale Barbosa GuerraPrograma de Pós Graduação em Medicina Tropical, Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.
João Marcos Bemfica Barbosa FerreiraPrograma de Pós Graduação em Medicina Tropical, Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.
Jorge Augusto de Oliveira GuerraPrograma de Pós Graduação em Medicina Tropical, Escola de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus, Brazil.
Fundação de Medicina Tropical · BREscola Superior de Ciências da Saúde · BRUniversidade Federal do Amazonas · BRUniversidade de Ribeirão Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the Brazilian Amazon, a new epidemiological profile of Chagas disease transmission, the oral route, has been detected and cited as being responsible for the increase in acute cases in Brazil. The clinical evaluation of acute Chagas disease (ACD) has been a challenge since it can progress to a chronic phase with cardiac alterations, and the follow-up by modern diagnostic methods is very difficult due to the socio-geographical characteristics of the Brazilian Amazon. Thus, alternatives should be sought to alleviate this problem. We conducted a study to evaluate subjects with ACD using the 12-lead ECG QRS score (Selvester score) as an estimative of myocardial injury progression before and after ACD treatment.

methodsThe study included indigenous subjects from the Amazon region with ACD in clinical follow-up at the Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (FMT-HVD) Chagas Disease outpatient clinic in the state of Amazonas, Brazil. The control group consisted of 31 healthy volunteers with no history of heart disease and no reactive serology for Chagas disease. Baseline ECG was performed in all subjects. The Selvester scoring method was performed according to the standardized guide (< 3 points: no myocardial injury,> 3: points × 3% = % of the predicted LV infarction).

resultsA total of 62 subjects were included, 31 as cases and 31 as controls. The mean follow-up of the case group was 17 months. The control group presented normal ECG. The case group presented 13 alterations before treatment and 11 after. Nineteen individuals presented scores > 3 points, 6 before and 13 after. In 19.36% of subjects, myocardial injury was found before treatment and in 41.94% after treatment.

conclusionThis is the first study that uses the Selvester score (SS) to predict myocardial injury in subjects with ACD. The results of this study suggest the significant presence of myocardial injury from the beginning of treatment to the period post treatment of ACD, which demonstrates that the SS can be applied for stratification and follow-up of Chagas disease in the Amazon region.

Indexed as

AdultBrazilChagas DiseaseCoronary Artery DiseaseElectrocardiographyFemaleHeartHumansIndigenous PeoplesLongitudinal StudiesMaleMiddle AgedBrazilian AmazonChagas diseaseMyocardial injurySelvester score

Identifiers

PMID33926389
PMCPMC8082885
OpenAlexW3158974038

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.