Evidence map›Paper›PMID 33926105›Full record

ReviewJournal of clinical medicine2021

Autoinflammatory Features in Gouty Arthritis.

Paola Galozzi, Sara Bindoli, Andrea Doria, Francesca Oliviero, Paolo Sfriso

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 103 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Clinical observations on arthroscopic removal of urate deposits in the knee: a seven-case series.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. NETs: a new target for autoimmune disease.Frontiers in immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Paola GalozziRheumatology Unit, Department of Medicine-DIMED, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-8228-2069
Sara BindoliRheumatology Unit, Department of Medicine-DIMED, University of Padova, 35128 Padova, Italy.
Andrea DoriaRheumatology Unit, Department of Medicine-DIMED, University of Padova, 35128 Padova, Italy.ORCID 0000-0003-0548-4983
Francesca OlivieroRheumatology Unit, Department of Medicine-DIMED, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-4958-5105
Paolo SfrisoRheumatology Unit, Department of Medicine-DIMED, University of Padova, 35128 Padova, Italy.ORCID 0000-0001-6432-7174
University of Padua · IT

Funding

Università degli Studi di Padova DOR2033958/20
6 · The paper itself

Abstract

In the panorama of inflammatory arthritis, gout is the most common and studied disease. It is known that hyperuricemia and monosodium urate (MSU) crystal-induced inflammation provoke crystal deposits in joints. However, since hyperuricemia alone is not sufficient to develop gout, molecular-genetic contributions are necessary to better clinically frame the disease. Herein, we review the autoinflammatory features of gout, from clinical challenges and differential diagnosis, to the autoinflammatory mechanisms, providing also emerging therapeutic options available for targeting the main inflammatory pathways involved in gout pathogenesis. This has important implication as treating the autoinflammatory aspects and not only the dysmetabolic side of gout may provide an effective and safer alternative for patients even in the prevention of possible gouty attacks.

Indexed as

autoinflammationgoutIL-1 inhibitorstherapy

Identifiers

PMID33926105
PMCPMC8123608
OpenAlexW3158205771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.