Evidence map›Paper›PMID 33926046›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period.

Caroline Burgard, Robert Stahl, Giovanna Negrao de Figueiredo, Julien Dinkel, Thomas Liebig, Dania Cioni, Emanuele Neri, Christoph G Trumm

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Caroline BurgardDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.
Robert StahlInstitute for Diagnostic and Interventional Neuroradiology, University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0003-2788-9316
Giovanna Negrao de FigueiredoDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, Germany.
Julien DinkelDepartment of Radiology, University Hospital, LMU Munich, 81377 Munich, Germany.
Thomas LiebigInstitute for Diagnostic and Interventional Neuroradiology, University Hospital, LMU Munich, 81377 Munich, Germany.
Dania CioniDepartment of Translational Research, University of Pisa, Via Roma 67, 56126 Pisa, Italy.ORCID 0000-0002-5120-886X
Emanuele NeriDepartment of Translational Research, University of Pisa, Via Roma 67, 56126 Pisa, Italy.ORCID 0000-0001-7950-4559
Christoph G TrummInstitute for Diagnostic and Interventional Neuroradiology, University Hospital, LMU Munich, 81377 Munich, Germany.
LMU Klinikum · DEUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate technical outcome, diagnostic yield and safety of computed tomographic fluoroscopy-guided percutaneous core needle biopsies in patients with mediastinal masses.

methodsOverall, 155 CT fluoroscopy-guided mediastinal core needle biopsies, performed from March 2010 to June 2020 were included. Size of lesion, size of needle, access path, number of success, number of biopsies per session, diagnostic yield, patient's position, effective dose, rate of complications, tumor localization, size of tumor and histopathological diagnosis were considered. Post-interventional CT was performed, and patients observed for any complications. Complications were classified per the Society of Interventional Radiology (SIR).

results148 patients (age, 54.7 ± 18.2) underwent 155 CT-fluoroscopy-guided percutaneous biopsies with tumors in the anterior (114; 73.5%), middle (17; 11%) and posterior (24; 15.5%) mediastinum, of which 152 (98%) were technically successful. For placement of the biopsy needle, in 82 (52.9%) procedures a parasternal trajectory was chosen, in 36 (23.3%) a paravertebral access, in 20 (12.9%) through the lateral intercostal space and in 17 (11%) the thoracic anterior midline, respectively. A total of 136 (89.5%) of the biopsies were considered adequate for a specific histopathologic analysis. Total DLP (dose-length product) was 575.7 ± 488.8 mGy*cm. Mean lesion size was 6.0 ± 3.3 cm. Neoplastic pathology was diagnosed in 115 (75.7%) biopsies and 35 (23%) biopsy samples showed no evidence of malignancy. Minor complications were observed in 18 (11.6%) procedures and major pneumothorax requiring drainage insertion in 3 interventions (1.9%).

conclusionCT fluoroscopy-guided percutaneous core needle biopsy of mediastinal masses is an effective and safe procedure for the initial assessment of patients with mediastinal tumors.

Indexed as

core needle biopsyCT-guided biopsyinterventional radiologymediastinal mass

Identifiers

PMID33926046
PMCPMC8144979
OpenAlexW3159679237

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.